Results 111 to 120 of about 10,144,475 (264)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Fractional regression models for second stage DEA efficiency analyses [PDF]

open access: yes
Data envelopment analysis (DEA) is commonly used to measure the relative efficiency of decision-making units. Often, in a second stage, a regression model is estimated to relate DEA efficiency scores to exogenous factors. In this paper, we argue that the
Joaquim J.S. Ramalho   +2 more
core  

Model selection in generalised structured additive regression models [PDF]

open access: yes, 2007
In recent years data sets have become increasingly more complex requiring more flexible instruments for their analysis. Such a flexible instrument is regression analysis based on a structured additive predictor which allows an appropriate modelling for ...
Belitz, Christiane
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Bayesian and maximin optimal designs for heteroscedastic regression models [PDF]

open access: yes
The problem of constructing standardized maximin D-optimal designs for weighted polynomial regression models is addressed. In particular it is shown that, by following the broad approach to the construction of maximin designs introduced recently by Dette,
Dette, Holger   +2 more
core  

Quantitative Methods for Evaluating the Informal Economy. Case Study at the Level of Romania [PDF]

open access: yesTheoretical and Applied Economics, 2010
The evaluation of the hidden economy involves major difficulties related to the use of an adequate methodology and to ensuring the necessary database for estimating some econometric models and some economic variables.
Tudorel ANDREI   +2 more
doaj  

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Mixture of bivariate Poisson regression models with an application to insurance [PDF]

open access: yes
In a recent paper Bermúdez [2009] used bivariate Poisson regression models for ratemaking in car insurance, and included zero-inflated models to account for the excess of zeros and the overdispersion in the data set. In the present paper, we revisit this
Lluís Bermúdez, Dimitris Karlis
core  

The extreme residuals in logistic regression models [PDF]

open access: yes, 1985
Goodness of fit tests for logistic regression models using extreme residuals are considered. Moment properties of the Pearson residuals are developed and used to define modified residuals, for the cases when the model fit is made by maximum ...
Z. Al-sarraf   +3 more
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

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