Results 101 to 110 of about 10,144,475 (264)
A priori ratemaking using bivariate poisson regression models [PDF]
In automobile insurance, it is useful to achieve a priori ratemaking by resorting to generalized linear models, and here the Poisson regression model constitutes the most widely accepted basis. However, insurance companies distinguish between claims with
Lluis Bermúdez i Morata
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Predictive Modeling of Urban Travel Demand Using Neural Networks and Regression Analysis
Urban ScienceUrban transportation systems are increasingly strained by population growth, changing mobility patterns, and the need for sustainable infrastructure planning.
Muhammed Ali Çolak, Osman Ünsal Bayrak
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
WorldThis study estimates the impact of some socio-economic, real estate, and accessibility factors on the demographic change of the Italian provinces. Migration rates were analysed for one hundred and thirteen provincial capitals, or former provincial ...
Antonio Basile, Mariano Gallo
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Photoluminescent Device for Monitoring Fusarium Infection in Seeds
Сельскохозяйственные машины и технологииPlant diseases reduce crop yields and can significantly undermine the sustainability of the agricultural sector. Early detection is crucial for effective disease control and management.
M. N. Moskovsky +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Endogeneity in Logistic Regression Models
Emerging Infectious Diseases, 2005 George Avery +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Efficient design of experiment for exponential regression models [PDF]
In this paper robust and efficient designs are derived for several exponential decay models. These models are widely used in chemistry, pharmacokinetics or microbiology.
Dette, Holger +3 more
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