Results 81 to 90 of about 2,028,100 (318)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
BioResources, 2023 Tropical species are widely used in construction, and their physical and mechanical properties have been important characteristics with direct impact on the design of structures, especially the strength and stiffness of wood applied in them.
Heloiza Candeia Ruthes +10 more
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Automatic Classification Of Voice Quality: Comparing
, 2008 In this paper, two methods for automatically classifying voice quality are compared: regression analysis and hidden Markov models (HMMs). The findings of this research show that HMMs can be used to classify voice quality.
Regression Models And, Mirjam Wester
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Variable Selection and Model Choice in Geoadditive Regression Models [PDF]
, 2007 Model choice and variable selection are issues of major concern in practical regression analyses. We propose a boosting procedure that facilitates both tasks in a class of complex geoadditive regression models comprising spatial effects, nonparametric ...
Kneib, Thomas +2 more
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Effect of BOF slag composition on the end-point[C]content of ultra-low carbon steel
工程科学学报, 2015 The effect of slag composition on the[C] content of ultra-low carbon steel at the end of smelting was investigated by the coexistence theory,dynamics analysis and experimental verification.
ZHANG Ming-bo +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Efficient Regression in Time Series Partial Linear Models [PDF]
This paper studies efficient estimation of partial linear regression in time series models. In particular, it combines two topics that have attracted a good deal of attention in econometrics, viz.
Peter C.B. Phillips +2 more
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
A fitter use of Monte Carlo simulations in regression models [PDF]
Computational Ecology and Software, 2011 In this article, I focus on the use of Monte Carlo simulations (MCS) within regression models, being this application very frequent in biology, ecology and economy as well. I'm interested in enhancing a typical fault in this application of MCS, i.e.
Alessandro Ferrarini
doaj