Results 71 to 80 of about 2,028,100 (318)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Efficient quantile regression for heteroscedastic models

open access: yes, 2015
Quantile regression (QR) provides estimates of a range of conditional quantiles. This stands in contrast to traditional regression techniques, which focus on a single conditional mean function. Lee et al.
MacEachern, Steve N,   +9 more
core   +1 more source

Bayesian Varying-coefficient Models using Adaptive Regression Splines [PDF]

open access: yes, 2000
Varying-coefficient models provide a flexible framework for semi- and nonparametric generalized regression analysis. We present a fully Bayesian B-spline basis function approach with adaptive knot selection.
Ludwig Fahrmeir   +3 more
core   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Regression Models for Lean Production [PDF]

open access: yes, 2017
Data mining models are an excellent tool to help companies that live from the sales of items they produce because it allows the company to optimize its production and reduce costs, for example in storage. When these models are combined with Lean Production, it becomes easier to remove waste and optimize industrial production.
Ricardo Bragança   +2 more
openaire   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Regression Models of Atlas Appearance [PDF]

open access: yes, 2009
Models of object appearance based on principal components analysis provide powerful and versatile tools in computer vision and medical image analysis. A major shortcoming is that they rely entirely on the training data to extract principal modes of appearance variation and ignore underlying variables (e.g., subject age, gender).
Torsten Rohlfing   +2 more
openaire   +2 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Predictive Models of Adult Distance Learners' Academic Performance: Comparative Analysis of Two Regression-based Models of Path Analysis

open access: yes, 2011
Using two regression-based models, this study looked into factors that explain academic performance of adult distance learners. The efficiency and applicability of linear regression and logit regression procedures as statistical models for path analysis ...
Quimbo, Maria Ana T.
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy