Results 221 to 230 of about 142,236 (313)

Mechanistic Learning for Predicting Survival Outcomes in Head and Neck Squamous Cell Carcinoma

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 540-550, March 2025.
ABSTRACT We employed a mechanistic learning approach, integrating on‐treatment tumor kinetics (TK) modeling with various machine learning (ML) models to address the challenge of predicting post‐progression survival (PPS)—the duration from the time of documented disease progression to death—and overall survival (OS) in Head and Neck Squamous Cell ...
Kevin Atsou, Anne Auperin, Jôel Guigay, Sébastien Salas, Sebastien Benzekry   +4 more
wiley   +1 more source

Pharmacodynamic Comparison of Ceftolozane/Tazobactam and Ceftazidime/Avibactam, Administered by Intermittent or Continuous Infusion, Against a Clinical Isolate of Carbapenem-Resistant <i>Pseudomonas aeruginosa</i> Producing GES <i>β</i>-Lactamase in a Hollow Fiber Infection Model. [PDF]

Pharmaceutics
Ahn TK, Kwack WG, Im SY, Moon SH, Park SJ, Park KH, Chung EK.   +6 more
europepmc   +1 more source

A Multiple‐Model‐Informed Drug‐Development Approach for Optimal Regimen Selection of an Oncolytic Virus in Combination With Pembrolizumab

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 572-582, March 2025.
ABSTRACT The antitumor efficacy of an intratumoral injection of a genetically engineered oncolytic vaccinia virus carrying human IL‐7 and murine IL‐12 genes (hIL‐7/mIL‐12‐VV) was demonstrated in CT26.WT‐bearing mice. In the CT26.WT‐bearing mouse model, the efficacy of the combination of hIL‐7/mIL‐12‐VV plus the anti‐programmed cell death protein (PD)‐1
Akihiro Yamada, Mary P. Choules, Frances A. Brightman, Shigeru Takeshita, Shinsuke Nakao, Nobuaki Amino, Takeshi Nakayama, Masato Takeuchi, Kanji Komatsu, Fernando Ortega, Hitesh Mistry, David Orrell, Christophe Chassagnole, Peter L. Bonate   +13 more
wiley   +1 more source

Case Report: Vitiligo and Alopecia Universalis Following Rituximab Therapy in a Patient with Myasthenia Gravis. [PDF]

Clin Cosmet Investig Dermatol
Alzahrani D, Niaz G, Roblah TM, Al-Osaimi AK, Alsulaimani H.   +4 more
europepmc   +1 more source

Strategies for Assessing Post‐Wildfire Geomorphic Resilience in Semiarid Rivers

River Research and Applications, EarlyView.
ABSTRACT We review and summarize diverse components of a catchment that can be monitored after wildfire to assess the geomorphic resilience of the river corridor in semiarid regions. We distinguish upland portions of river catchments from river corridors.
Ellen Wohl, Shayla Triantafillou, Alex Thornton‐Dunwoody, Connor Mertz, Katie Larkin, William Keenan, Steven Griffin, Dylan Davis, Lindsey Blehm   +8 more
wiley   +1 more source

Can phage-antibiotic combinations overcome uropathogenic Escherichia coli regrowth? evidence from in vitro and in vivo models. [PDF]

Virol J
Makky S, Hussein AH, Mohamed AA, Essam K, Agwa MM, ElAziz MMA, El-Shibiny A.   +6 more
europepmc   +1 more source

Wall‐to‐wall Amazon forest height mapping with Planet NICFI, Aerial LiDAR, and a U‐Net regression model

Remote Sensing in Ecology and Conservation, EarlyView.
Tree canopy height is a key indicator of forest biomass and structure, yet accurate mapping across the Amazon remains challenging. Here, we generated a canopy height map of the Amazon forest at ~4.8 m resolution using Planet NICFI imagery and a deep learning U‐Net model trained with airborne LiDAR data.
Fabien H. Wagner, Ricardo Dalagnol, Griffin Carter, Mayumi C. M. Hirye, Shivraj Gill, Le Bienfaiteur Sagang Takougoum, Samuel Favrichon, Michael Keller, Jean P. H. B. Ometto, Lorena Alves, Cynthia Creze, Stephanie P. George‐Chacon, Shuang Li, Zhihua Liu, Adugna Mullissa, Yan Yang, Erone G. Santos, Sarah R. Worden, Martin Brandt, Philippe Ciais, Stephen C. Hagen, Sassan Saatchi   +21 more
wiley   +1 more source

Locally advanced rectal cancer: what patients and practitioners should know about non-operative management. [PDF]

EClinicalMedicine
Tosi F, Patelli G, Carnevali P, Bracco F, Amatu A, Bencardino K, Bonazzina EF, Mauri G, Piscazzi D, Villa F, Sartore-Bianchi A, Siena S.   +11 more
europepmc   +1 more source

Improving forest age estimation to understand subtropical forest regrowth dynamics using deep learning image segmentation of time‐series historical aerial photographs

Remote Sensing in Ecology and Conservation, EarlyView.
Accurately estimating forest age is key to understanding how forests recover and evaluating restoration success. We developed a two‐step deep learning approach using historical greyscale aerial photographs to map forest age at fine spatial scales. By combining a pre‐trained model with localized fine‐tuning, our U‐Net + ResNet50 architecture achieved ...
Ying Ki Law, Yi‐Fei Gu, Shuwen Liu, Guangqin Song, Aland H. Y. Chan, Cham Man Tse, Zhonghua Liu, Martha J. Ledger, Billy C. H. Hau, Sawaid Abbas, Jin Wu   +10 more
wiley   +1 more source

Treatment and Prevention of Traumatic Eyebrow Cicatricial Alopecia With Stem Cell Growth Serum. [PDF]

Plast Reconstr Surg Glob Open
Ong KHX, Lee SJ.
europepmc   +1 more source