Results 121 to 130 of about 7,627,633 (340)
HOW TO STIMULATE STUDENTS TO REGULAR WORK DURING THE SEMESTER
Высшее образование в России, 2022 We consider a set of specific incentives to encourage regular, systematic learning by students an educational material during the semester. Among them are the following: more liberal, friendly atmosphere, possibility of pre-term examination, taking into ...
Mikhail A. Prikhodovsky
doaj
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Arquivos de Neuro-Psiquiatria, 2006 MOTIVO: O impacto causado pela cefaléia pode impedir a aderência a um programa regular de atividade física. OBJETIVO: Avaliar a prevalência e as características da cefaléia em uma população de praticantes de exercícios físicos.
Fabrício Miranda +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
, 1980 The term polylinks is proposed for structures made of straight rods joined at their ends into rings of polygonal form which are linked through one another to provide rigidity. The structures are regular when the polygons are regular and all of the same species and size, and the corners of the structures are all alike in location and surroundings ...
openaire +3 more sources
Categorical structures enriched in a quantaloid: regular presheaves, regular semicategories
, 2004 We study presheaves on semicategories enriched in a quantaloid: this gives rise to the notion of regular presheaf. A semicategory is regular when its representable presheaves are regular, and its regular presheaves then constitute an essential (co ...
Stubbe, Isar
core
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
On Error Bound Moduli for Locally Lipschitz and Regular Functions [PDF]
, 2016 Minghua Li, Kaiwen Meng, Xiaoqi Yang
openalex +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source