Results 101 to 110 of about 382,965 (288)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Highly Parallel Regular Expression Matching Using a Real Processing-in-Memory System

open access: yesIEEE Access
Processing-in-Memory (PIM) is an emerging computing paradigm exploiting a cutting-edge memory device (PIM device) that integrates hundreds to thousands of processing units with the memory modules. A data-intensive application running in a host system can
Jeonghyeon Joo   +4 more
doaj   +1 more source

Regular Expressions for PCTL Counterexamples

open access: green, 2008
Berteun Damman   +2 more
openalex   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Optimasi String Matching Dengan Menerapkan Regular Expression Pada Java

open access: yesJurnal Eksplora Informatika, 2011
Algoritma string matching semakin berkembang dan masing-masing algoritma tersebut memiliki keunggulan. Salah satu metode string matching yang ada yaitu regular expression.
Rani Purbaningtyas
doaj  

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