Results 101 to 110 of about 551,541 (325)
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin+14 more
wiley +1 more source
Facing the demand of multi-domain security control in the integrated network of air and ground, to solve the problem that singleprocess regular matching restricts the performance of interconnected security gateway, the method of high-performance ...
Bo LU, Yueming LU
doaj +2 more sources
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita+1 more
wiley +1 more source
Containment of Nested Regular Expressions [PDF]
Nested regular expressions (NREs) have been proposed as a powerful formalism for querying RDFS graphs, but research in a more general graph database context has been scarce, and static analysis results are currently lacking. In this paper we investigate the problem of containment of NREs, and show that it can be solved in PSPACE, i.e., the same ...
arxiv
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi+5 more
wiley +1 more source
A Polynomial Time Match Test for Large Classes of Extended Regular Expressions [PDF]
In the present paper, we study the match test for extended regular expressions. We approach this NP-complete problem by introducing a novel variant of two-way multihead automata, which reveals that the complexity of the match test is determined by a hidden combinatorial property of extended regular expressions, and it shows that a restriction of the ...
arxiv
Programming Techniques: Regular expression search algorithm [PDF]
Thompson Ken
openalex +1 more source
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane+16 more
wiley +1 more source
Novel NFA engine construction method of regular expressions
A novel method for constructing smaller non-deterministic finite automata (NFA) engine from given regular expressions named PFA was proposed.There are three main algorithms in PFA,the pretreatment algorithm,the coding parser tree algorithm and the NFA ...
Mao-hua JING+3 more
doaj