Results 101 to 110 of about 7,225,806 (376)

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Particle motion and collisions around rotating regular black hole

, 2014
The neutral particle motion around rotating regular black hole that was derived from the Ay\'{o}n-Beato-Garc\'{i}a black hole solution by the Newman-Janis algorithm in the preceding paper [Phys. Rev. D 89, 104017, (2014)] has been studied.
Abdujabbarov, Ahmadjon, Ahmedov, Bobomurat, Stuchlík, Zdenek, Toshmatov, Bobir   +3 more
core   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

The regular part of second-order differential sectorial forms with lower-order terms

, 2013
We present a formula for the regular part of a sectorial form that represents a general linear second-order differential expression that may include lower-order terms. The formula is given in terms of the original coefficients.
Sauter, Manfred, ter Elst, A. F. M.
core   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

NUWT: JAWI-SPECIFIC BUCKWALTER CORPUS FOR MALAY WORD TOKENIZATION

Journal of ICT, 2016
This paper describes the design and creation of a monolingual parallel corpus for the Malay language written in Jawi. This paper proposes a new corpus called the National University of Malaysia Word Tokenization (NUWT) corpora To the best of our ...
Juhaida Abu Bakar, Khairuddin Omar, Mohammad Faidzul Nasrudin, Mohd Zamri Murah   +3 more
doaj  

Combining globally search for a regular expression and print matching lines with bibliographic monitoring of genomic database improves diagnosis. [PDF]

Front Genet, 2023
Tran Mau-Them F, Overs A, Bruel AL, Duquet R, Thareau M, Denommé-Pichon AS, Vitobello A, Sorlin A, Safraou H, Nambot S, Delanne J, Moutton S, Racine C, Engel C, De Giraud d'Agay M, Lehalle D, Goldenberg A, Willems M, Coubes C, Genevieve D, Verloes A, Capri Y, Perrin L, Jacquemont ML, Lambert L, Lacaze E, Thevenon J, Hana N, Van-Gils J, Dubucs C, Bizaoui V, Gerard-Blanluet M, Lespinasse J, Mercier S, Guerrot AM, Maystadt I, Tisserant E, Faivre L, Philippe C, Duffourd Y, Thauvin-Robinet C.   +40 more
europepmc   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Low-power TCAM for regular expression matching

Tongxin xuebao, 2014
A character-indexed regular expression matching algorithm was presented to address the limitations of TCAM power consumption. This algorithm used the idea of separating the alphabet table from the states in deterministic finite automaton (DFA) for ...
Lin-xuan DING, Kun HUANG, Da-fang ZHANG
doaj   +2 more sources

Offset-FA: A Uniform Method to Handle Both Unbounded and Bounded Repetitions in Regular Expression Matching. [PDF]

Sensors (Basel), 2022
Xu C, Yu K, Xu X, Bao X, Wu S, Zhao B.
europepmc   +1 more source