Results 121 to 130 of about 5,692,247 (342)
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
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Molecular Oncology, EarlyView.Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla +5 more
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Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
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Disambiguation of Regular Expressions with Backreferences via Term Rewriting
Моделирование и анализ информационных системIn this paper we focus on regular expressions with acyclic backreferences and treat them as a semiring satisfying certain theorems of Kleene algebra. Using these theorems as term rewriting rules, we introduce an algorithm for memory disambiguation of ...
Daria N. Ismagilova +1 more
doaj +1 more source
Regular expressions into finite automata
Theoretical Computer Science, 1993 It is well-known that the regular expressions can be translated into non- deterministic finite automata \((NFA)\) with or without \(\lambda\)- transitions. The standard method first translate a regular expression, in linear time, into an NFA with \(\lambda\)-transitions and then the \(\lambda\)-transitions are eliminated in quadratic time.
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Molecular Oncology, EarlyView.mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo +8 more
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Programming Techniques: Regular expression search algorithm [PDF]
, 1968 Thompson Ken
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Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
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Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
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, 2018 This slide deck was presented at the Library Carpentry Workshop at SUB Hamburg on Nov 5 2018. Please note: This presentation is incomplete without the oral speech.
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