Results 71 to 80 of about 7,066,247 (260)
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
, 2007 The purpose of this paper is to study a new class of rings R in which, for each a Î R, aÎ aR aR, for some positive integer n. Such rings are called sp-weakly regular rings and give some of their basic properties as well as the relation between sp-weakly
Abdullah Abdul-Jabbar, Raida Mahmood
core +1 more source
Super-regularity in local rings
Journal of Pure and Applied Algebra, 1976 for which the bi-functor Extz(-, -) is non-vanishing) is quite independent from the weak (or Tor -) dimension of A (i.e. the last integer n for which the bi-functor Tort (-, -) is non-vanishing). En this note we show that equality of these dimensions in local rings is related to phenorn- ena of finiteness of prime ideals.
openaire +1 more source
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Directed unions of local quadratic transforms of a regular local ring
Journal of Algebra, 2017 We consider the directed union S of an infinite sequence {(R_n, m_n)} of successive local quadratic transforms of a regular local ring (R, m). If dim R = 2, Abhyankar proves that S is a valuation ring. If dim R > 2, Shannon gives necessary and sufficient conditions for S to be a rank 1 valuation domain and Granja gives necessary and sufficient ...
Heinzer, William +2 more
openaire +3 more sources
Aging and Cancer, EarlyView.This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source
Sequence-regular commutative DG-rings [PDF]
We introduce a new class of commutative noetherian DG-rings which generalizes the class of regular local rings. These are defined to be local DG-rings $(A,\bar{\mathfrak{m}})$ such that the maximal ideal $\bar{\mathfrak{m}} \subseteq \mathrm{H}^0(A)$ can
Shaul, Liran
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak +4 more
wiley +1 more source