Results 41 to 50 of about 804 (216)
Strongly Maximal Submodules with A Study of Their Influence on Types of Modules
Ibn Al-Haitham Journal for Pure and Applied Sciences, 2022 Let S be a commutative ring with identity, and A is an S-module. This paper introduced an important concept, namely strongly maximal submodule. Some properties and many results were proved as well as the behavior of that concept with its localization was
Fatima M. Mohialdeen, Buthyna N. Shihab
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The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
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The ring of k-regular sequences
Theoretical Computer Science, 1990 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Jean-Paul Allouche, Jeffrey O. Shallit
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Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Classification of Boolean algebras through von Neumann regular $\mathcal{C}^{\infty}-$rings [PDF]
Categories and General Algebraic Structures with ApplicationsIn this paper, we introduce the concept of a ``von Neumann regular $\mathcal{C}^{\infty}$-ring", which is a model for a specific equational theory.
Jean Berni, Hugo Mariano
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On GP-InjectivityWith Some Types of Rings [PDF]
مجلة التربية والعلم, 2007 The purpose of this paper is to study GP-injective modules and give some of it is properties. Also, we proved: (1) If every simple right R-module is GP-injective, and R is reversible ring, then R is a right weakly -regular.
Abdullah M. Abdul-Jabbar +1 more
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J-Regular Rings with Injectivities [PDF]
Algebra Colloquium, 2013 Let R be a J-regular ring, i.e., R/J(R) is a von Neumann regular ring, where J(R) is the Jacobson radical of R. It is proved: (i) For every n ≥ 1, R is right n-injective if and only if every homomorphism from an n-generated small right ideal of R to RR can be extended to one from RR to RR.
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Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source