Results 51 to 60 of about 1,320,247 (288)
The ring of k-regular sequences
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Jean-Paul Allouche, Jeffrey O. Shallit
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Invo-regular unital rings [PDF]
It was asked by Nicholson (Comm. Algebra, 1999) whether or not unit-regular rings are themselves strongly clean. Although they are clean as proved by Camillo-Khurana (Comm. Algebra, 2001), recently Nielsen and Ster showed in Trans. Amer. Math. Soc., 2018
Danchev, Peter V.
core +2 more sources
In our study we examine definition of strongly γ -regular rings and associates, investigate interplay between strongly γ - regular rings and other reduced rings. We also study GP – injective modules, and discuss its relation with strongly
Luma Ahmed Khaleel, Beyda S. Abdullah
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Strongly Semiunits and Tri-Regular Elements in Rings [PDF]
In this paper we study semiunit elements in the group ring Z2G, where G is a cyclic group and we introduce and discuss strongly semiunit elements in Zn, for n=p, 2p, p2 where p is an odd prime.
Parween Ali Hummadi , Suham Hamad Awla
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J-Regular Rings with Injectivities [PDF]
Let R be a J-regular ring, i.e., R/J(R) is a von Neumann regular ring, where J(R) is the Jacobson radical of R. It is proved: (i) For every n ≥ 1, R is right n-injective if and only if every homomorphism from an n-generated small right ideal of R to RR can be extended to one from RR to RR.
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Rings Over Which Certain Modules Are YJ-Injective [PDF]
In this paper we continue to study the concept of YJ-injectivity which was first introduced by Ming in 1985. Furthermore, we give some characterizations and properties for it.
Abdullah M. Abdul-Jabbar
doaj +1 more source

