Results 71 to 80 of about 1,320,247 (288)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Exchange rings in which all regular elements are one-sided unit-regular [PDF]

open access: yes, 2008
summary:Let $R$ be an exchange ring in which all regular elements are one-sided unit-regular. Then every regular element in $R$ is the sum of an idempotent and a one-sided unit.
Chen, Huanyin
core   +1 more source

On n-flat modules and n-Von Neumann regular rings

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2006
We show that each R-module is n-flat (resp., weakly n-flat) if and only if R is an (n,n−1)-ring (resp., a weakly (n,n−1)-ring). We also give a new characterization of n-Von Neumann regular rings and a characterization of weak n-Von Neumann regular rings ...
Najib Mahdou
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Pathological modules over tame rings [PDF]

open access: yes, 1976
Brenner S, Ringel CM. Pathological modules over tame rings. Journal of the London Mathematical Society.
Ringel, Claus Michael, Brenner, Sheila
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Left 𝑊𝑀𝐶2 Rings

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2011
We introduce in this paper the concept of left 𝑊𝑀𝐶2 rings and concern ourselves with rings containing an injective maximal left ideal. Some known results for left idempotent reflexive rings and left 𝐻𝐼 rings can be extended to left 𝑊𝑀𝐶2 rings.
Junchao Wei
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

The structure of balanced rings [PDF]

open access: yes, 1973
Dlab V, Ringel CM. The structure of balanced rings. Proceedings of the London Mathematical Society.
Dlab, Vlastimil, Ringel, Claus Michael
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

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