Results 81 to 90 of about 38,836 (265)
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Nazar H. Shuker, Rani S. Younis
doaj +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
WJCP- الحلقات الغامرة من النمط
Raida D. Mahmood, Shahla M. Khalil
doaj +1 more source
On von Neumann regular rings - II.
As in other papers of this long series [for Part X see Collect. Math. 34, 81-94 (1983; Zbl 0544.16006), Part XIII see Ann. Univ. Ferrara, Nuova Ser., Sez. VII 31, 49-61 (1985; Zbl 0588.16006)], the author considers generalizations of concepts such as regularity and injectivity.
openaire +16 more sources
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
حول الحلقات المنتظمة من النمط-m
Zubayda M. Ibraheem, Maha F. Khalaf
doaj +1 more source

