Results 101 to 110 of about 1,719,198 (279)

Classification of Conceptual Variation of Terms Based on the Semantic Discursive Modulation

Ikala: Revista de Lenguaje y Cultura, 2011
This paper describes a proposal to classify the conceptual variation of terms represented by regular and irregular polysemic processes to which terms as lexical units are subjected in discourse.
Irina Kostina
doaj  

Adaptive Estimates of Parameters of Regular Variation

The Annals of Statistics, 1985
The problem of estimating shape and scale parameters for a distribution with regularly varying tails is related to that of nonparametrically estimating a density at a fixed point, in that optimal construction of the estimators depends substantially upon unknown features of the distribution. We show how to overcome this problem by using adaptive methods.
Hall, Peter, Welsh, A. H.
openaire   +3 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Anatomical variation of the superficial branch of the radial nerve and brachioradialis tendon: a case report with embryological and clinical insights [PDF]

Folia Medica
Anatomical variation of the peripheral nerves are important because they may have therapeutic implications. The variation of the brachioradialis muscle (BRM) and the superficial branch of the radial nerve (SBRN) was noted during a regular teaching ...
Anand Verma, Seema Singh, Dibakar Borthakur, Harisha Kusuma   +3 more
doaj   +3 more sources

Regular Variation and the Identification of Generalized Accelerated Failure-Time Models [PDF]

Ridder (1990) provides an identification result for the Generalized Accelerated Failure-Time (GAFT) model. We point out that Ridder's proof of this result is incomplete, and provide an amended proof with an additional necessary and sufficient condition ...
Abbring, J.H., Ridder, G.
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Boundary blow-up solutions to semilinear elliptic equations with nonlinear gradient terms

Electronic Journal of Differential Equations, 2014
In this article we study the blow-up rate of solutions near the boundary for the semilinear elliptic problem $$\displaylines{ \Delta u\pm |\nabla u|^q=b(x)f(u), \quad x\in\Omega,\cr u(x)=\infty, \quad x\in\partial\Omega, }$$ where $\Omega$ is a ...
Shufang Liu, Yonglin Xu
doaj  

CDKN2A copy number alteration in bladder cancer: Integrative analysis in patient-derived xenografts and cancer patients

Molecular Therapy: Oncology
Bladder cancer (BlCa) is an extensively heterogeneous disease that leads to great variability in tumor evolution scenarios and lifelong patient surveillance, emphasizing the need for modern, minimally invasive precision medicine.
Maria-Alexandra Papadimitriou, Katerina-Marina Pilala, Konstantina Panoutsopoulou, Panagiotis Levis, Georgios Kotronopoulos, Zoi Kanaki, Gedeon Loules, Maria Zamanakou, Dimitrios Linardoutsos, Diamantis C. Sideris, Konstantinos Stravodimos, Apostolos Klinakis, Andreas Scorilas, Margaritis Avgeris   +13 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

DIVIDENDE ET REACTION BOURSIERE : UNE ETUDE ECONOMETRIQUE SUR LA BOURSE REGIONALE DES VALEURS MOBILIERES

Revue Economie, Gestion et Société, 2018
The objective of the present article is to analyze the influence of an announcement of variation of the regular dividend on the reaction of the Regional Stock market of the Movable Values (BRVM). We used secondary data descended of the files of the purse
Aboudou Ramanou YESSOUFOU
doaj   +1 more source