Results 121 to 130 of about 398,282 (297)

On scaling and regular variation

open access: yesPublications de l'Institut Mathematique, 2015
We survey scaling arguments, both asymptotic (involving regular variation) and exact (involving self-similarity), in various areas of mathematical analysis and mathematical physics.
openaire   +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

On regular variation of probability densities [PDF]

open access: yes
Regular variation of the tail of a multivariate probability distribution is implied by regular variation of the density f provided f satisfies a regularity condition.
Resnick, S., de Haan, L.
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Topological regular variation: III: Regular variation. [PDF]

open access: yes, 2008
This paper extends the topological theory of regular variation of the slowly varying case of [BOst13] to the regularly varying functions between metric groups, viewed as normed groups (see also [BOst14]). This employs the language of topological dynamics,
N. H. Bingham, A. J. Ostaszewski
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Survey on the deployment and design for regular topology structures in wireless sensor networks

open access: yesTongxin xuebao, 2012
In wireless sensor networks,such regular topology structures as Square,Hexagon and Triangle could fully cover the area to be monitored,provide accurate positioning for special events,and achieve better network performance.In order to provide valuable ...
Wen-xiang LI   +3 more
doaj   +2 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Lower Tail Dependence for Archimedean Copulas: Characterizations and Pitfalls [PDF]

open access: yes
Tail dependence copulas provide a natural perspective from which one can study the dependence in the tail of a multivariate distribution.For Archimedean copulas with continuously differentiable generators, regular variation of the generator near the ...
Charpentier, A., Segers, J.J.J.
core   +1 more source

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