Results 71 to 80 of about 668,979 (308)

Lithuanian on-line periodicals on the World Wide Web

Information Research: An International Electronic Journal, 2001
Deals with Lithuanian full-text electronic periodicals distributed through the World Wide Web. An electronic periodical is usually defined as a regular publication on some particular topic distributed in digital form, chiefly through the Web, but also by
Lina Sarlauskiene
doaj  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

ENTROPİ, ŞANS VE TANRI

Felsefe Dünyası, 2014
Evrenin bir başlangıcının olup olmadığı ya da bu düzenin nereden geldiğigibi sorular, insanlığın en büyük merakıdır. Fakat 18. Yüzyılda sanayi devrimininürünü olan buhar makinelerinin çalışma prensiplerinin keşfiyle birlikte doğan termodinamikve ...
Fatih Özgökman
doaj  

Regular, pseudo-regular, and almost regular matrices

, 2007
We give lower bounds on the largest singular value of arbitrary matrices, some of which are asymptotically tight for almost all matrices. To study when these bounds are exact, we introduce several combinatorial concepts. In particular, we introduce regular, pseudo-regular, and almost regular matrices.
openaire   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Nonoccurrence of Lavrentiev gap for a class of functionals with nonstandard growth

Advances in Nonlinear Analysis
We consider the functional ℱ(u)≔∫Ωf(x,Du(x))dx,{\mathcal{ {\mathcal F} }}\left(u):= \mathop{\int }\limits_{\Omega }f\left(x,Du\left(x)){\rm{d}}x, where f(x,z)f\left(x,z) satisfies a (p,q)\left(p,q)-growth condition with respect to zz and can be ...
De Filippis Filomena, Leonetti Francesco, Treu Giulia   +2 more
doaj   +1 more source

Regular Transition Functions and Regular Superprocesses [PDF]

Transactions of the American Mathematical Society, 1989
The class of regular Markov processes is very close to the class of right processes studied by Meyer, Getoor and others. We say that a transition function p p is regular if it is the transition function of a well-defined regular Markov process. A characterization of regular transition functions is given which implies that, if
openaire   +2 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Regularity of symbolic powers of square-free monomial ideals [PDF]

, 2021
Trương Thị Hiên, Trân Nam Trung
openalex   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source