Results 71 to 80 of about 832,966 (358)
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes+20 more
wiley +1 more source
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu+11 more
wiley +1 more source
This study aimed to identify determinants of quantitative dimensions of physical activity (PA; duration, frequency, and intensity) in community-dwelling, multi-morbid, older persons with cognitive impairment (CI).
Bastian Abel+8 more
doaj +1 more source
Lower bound for the regularity index of fat points
The problem to find an upper bound for the regularity index of fat points has been dealt with by many authors. In this paper we give a lower bound for the regularity index of fat points.
Van Thien, Phan
core +1 more source
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti+10 more
wiley +1 more source
Regularity for Semilinear Neutral Hyperbolic Equations with Cosine Families
The purpose of this paper is to obtain the regularity for solutions of semilinear neutral hyperbolic equations with the nonlinear convolution. The principal operator is the infinitesimal generator of a cosine and sine families.
Seong-Ho Cho, Jin-Mun Jeong
doaj +1 more source
Gradient estimates for the double phase problems in the whole space
This paper presents Calderón-Zygmund estimates for the weak solutions of a class of nonuniformly elliptic equations in $ \mathbb{R}^n $, which are obtained through the use of the iteration-covering method.
Bei-Lei Zhang , Bin Ge
doaj +1 more source
Local regularity for fractional heat equations
We prove the maximal local regularity of weak solutions to the parabolic problem associated with the fractional Laplacian with homogeneous Dirichlet boundary conditions on an arbitrary bounded open set $\Omega\subset\mathbb{R}^N$.
D Lamberton+16 more
core +1 more source
Regularity lemma for distal structures [PDF]
It is known that families of graphs with a semialgebraic edge relation of bounded complexity satisfy much stronger regularity properties than arbitrary graphs, and that they can be decomposed into very homogeneous semialgebraic pieces up to a small error
A. Chernikov, S. Starchenko
semanticscholar +1 more source
Iterative regularization for convex regularizers
We study iterative regularization for linear models, when the bias is convex but not necessarily strongly convex. We characterize the stability properties of a primal-dual gradient based approach, analyzing its convergence in the presence of worst case deterministic noise.
Cesare Molinari+3 more
openaire +3 more sources