Results 31 to 40 of about 2,593,342 (293)

CTCF and cohesin promote focal detachment of DNA from the nuclear lamina

Genome Biology, 2022
Background Lamina-associated domains (LADs) are large genomic regions that are positioned at the nuclear lamina. It has remained largely unclear what drives the positioning and demarcation of LADs.
Tom van Schaik, Ning Qing Liu, Stefano G. Manzo, Daan Peric-Hupkes, Elzo de Wit, Bas van Steensel   +5 more
doaj   +1 more source

α-Synuclein plasma membrane localization correlates with cellular phosphatidylinositol polyphosphate levels

eLife, 2021
The Parkinson’s disease protein α-synuclein (αSyn) promotes membrane fusion and fission by interacting with various negatively charged phospholipids. Despite postulated roles in endocytosis and exocytosis, plasma membrane (PM) interactions of αSyn are ...
Reeba Susan Jacob, Cédric Eichmann, Alessandro Dema, Davide Mercadante, Philipp Selenko   +4 more
doaj   +1 more source

A Genomic Analysis of Bacillus megaterium HT517 Reveals the Genetic Basis of Its Abilities to Promote Growth and Control Disease in Greenhouse Tomato

International Journal of Genomics, 2022
Bacillus megaterium is well known as a plant growth-promoting rhizobacterium, but the relevant molecular mechanisms remain unclear. This study aimed to elucidate the effects of B.
Wei Yang, Yingnan Zhao, Yang Yang, Minshuo Zhang, Xiaoxi Mao, Yanjie Guo, Xiangyu Li, Bu Tao, Yongzhi Qi, Li Ma, Wenju Liu, Bowen Li, Hong J. Di   +12 more
doaj   +1 more source

Assessing the impact of regulations and standards on innovation in the field of AI [PDF]

arXiv, 2023
Regulations and standards in the field of artificial intelligence (AI) are necessary to minimise risks and maximise benefits, yet some argue that they stifle innovation. This paper critically examines the idea that regulation stifles innovation in the field of AI.
arxiv  

Effects of chronic browsing on life‐history traits of an irruptive large herbivore population

Population Ecology, EarlyView.
This study aimed to determine the relationship between diet quality, body mass, and size (hind foot length), and female reproduction and sought to identify the mechanism by which high density under severe food limitations is maintained. Our results demonstrated that sika deer introduced to Nakanoshima Island have maintained high densities through high ...
Koichi Kaji, Kazutaka M. Takeshita, Hiroshi Takahashi, Hiromasa Igota, Mayumi Ueno, Yukiko Matsuura, Takashi Ikeda, Ryo Yoshizawa, Hino Takafumi, Tsuyoshi Yoshida   +9 more
wiley   +1 more source

Immunization with recombinant fusion of LTB and linear epitope (40–62) of epsilon toxin elicits protective immune response against the epsilon toxin of Clostridium perfringens type D

AMB Express, 2019
Epsilon toxin (Etx) produced by Clostridium perfringens types B and D, a major causative agent of enterotoxaemia causes significant economic losses to animal industry.
Himani Kaushik, Sachin Kumar Deshmukh, Amit Kumar Solanki, Bharti Bhatia, Archana Tiwari, Lalit C. Garg   +5 more
doaj   +1 more source

Irrigation has a higher impact on soil bacterial abundance, diversity and composition than nitrogen fertilization

Scientific Reports, 2021
The aim of this study was to assess the effects of irrigation frequency and nitrogen fertilization rate on the abundance, diversity, and composition of soil bacteria in winter wheat.
Haoran Li, Hongguang Wang, Bin Jia, Dongxiao Li, Qin Fang, Ruiqi Li   +5 more
doaj   +1 more source

Regulating the regulators

Journal of Experimental Medicine, 2009
Co-culture of PD-L1–expressing beads (red) and naive T cells (purple) promotes their conversion into T reg cells (green).
openaire   +3 more sources

Dendritic cells steering antigen and leukocyte traffic in lymph nodes

FEBS Letters, EarlyView.
Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta, Agnieszka Katarzyna Maciola, Tania Baccega, Giulia Pasqual   +3 more
wiley   +1 more source

Dynamic characteristics and functional analysis provide new insights into long non-coding RNA responsive to Verticillium dahliae infection in Gossypium hirsutum

BMC Plant Biology, 2021
Background Verticillium wilt is a widespread and destructive disease, which causes serious loss of cotton yield and quality. Long non-coding RNA (lncRNA) is involved in many biological processes, such as plant disease resistance response, through a ...
Guoning Wang, Xingfen Wang, Yan Zhang, Jun Yang, Zhikun Li, Lizhu Wu, Jinhua Wu, Nan Wu, Lixia Liu, Zhengwen Liu, Man Zhang, Liqiang Wu, Guiyin Zhang, Zhiying Ma   +13 more
doaj   +1 more source