Results 31 to 40 of about 8,776,825 (339)

A subset of conserved mammalian long non-coding RNAs are fossils of ancestral protein-coding genes

open access: yesGenome Biology, 2017
Background Only a small portion of human long non-coding RNAs (lncRNAs) appear to be conserved outside of mammals, but the events underlying the birth of new lncRNAs in mammals remain largely unknown.
Hadas Hezroni   +5 more
doaj   +1 more source

Capacity and tendency: A neuroscientific framework for the study of emotion regulation. [PDF]

open access: yes, 2019
It is widely accepted that the ability to effectively regulate one's emotions is a cornerstone of physical and mental health. As such, it should come as no surprise that the number of neuroimaging studies focused on emotion regulation and associated ...
Guassi Moreira, João F   +1 more
core   +2 more sources

A Genomic Analysis of Bacillus megaterium HT517 Reveals the Genetic Basis of Its Abilities to Promote Growth and Control Disease in Greenhouse Tomato

open access: yesInternational Journal of Genomics, 2022
Bacillus megaterium is well known as a plant growth-promoting rhizobacterium, but the relevant molecular mechanisms remain unclear. This study aimed to elucidate the effects of B.
Wei Yang   +12 more
doaj   +1 more source

Irrigation has a higher impact on soil bacterial abundance, diversity and composition than nitrogen fertilization

open access: yesScientific Reports, 2021
The aim of this study was to assess the effects of irrigation frequency and nitrogen fertilization rate on the abundance, diversity, and composition of soil bacteria in winter wheat.
Haoran Li   +5 more
doaj   +1 more source

Phenotyping Diabetes Mellitus on Aggregated Electronic Health Records from Disparate Health Systems

open access: yesPharmacoepidemiology, 2023
Background: Identifying patients with diabetes mellitus (DM) is often performed in epidemiological studies using electronic health records (EHR), but currently available algorithms have features that limit their generalizability.
Hui Xing Tan   +15 more
doaj   +1 more source

Quantifying Dynamic Regulation in Metabolic Pathways with Nonparametric Flux Inference [PDF]

open access: yes, 2019
One of the central tasks in systems biology is to understand how cells regulate their metabolism. Hierarchical regulation analysis is a powerful tool to study this regulation at the metabolic, gene-expression, and signaling levels.
He, Fei, Stumpf, Michael P H
core   +1 more source

SUMO: regulating the regulator.

open access: yesCell division, 2006
Post-translational modifiers of the SUMO (Small Ubiquitin-related Modifier) family have emerged as key regulators of protein function and fate. While the past few years have seen an enormous increase in knowledge on SUMO enzymes, substrates, and consequences of modification, regulation of SUMO conjugation is far from being understood. This brief review
Bossis, G., Melchior, F.
openaire   +4 more sources

Report on parallel proceedings [PDF]

open access: yes, 1999
Report of a Working Group considering the problems that arise from parallel proceedings, particularly in City fraud cases, within the national jurisdiction and ways in which those problems could be addressed.
Society for Advanced Legal Studies, Financial Regulation Working Group
core  

Evaluating the Genetic Overlap Between Congenital Heart Disease and Neuroblastoma Risk

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Children with congenital heart disease (CHD) have elevated neuroblastoma (NB) risk, potentially due to shared neural crest origins. We analyzed rare exonic de novo single‐nucleotide variants in 702 CHD and 454 NB trios from the Neuroblastoma Epidemiology in North America Study, Gabriella Miller Kids First Program, and a published cohort. Seven
Ji Yun Tark   +7 more
wiley   +1 more source

Citizen-science based study of the oral microbiome in Cystic fibrosis and matched controls reveals major differences in diversity and abundance of bacterial and fungal species

open access: yesJournal of Oral Microbiology, 2021
Introduction: Cystic fibrosis (CF) is an autosomal genetic disease, associated with the production of excessively thick mucosa and with life-threatening chronic lung infections. The microbiota of the oral cavity can act as a reservoir or as a barrier for
Jesse R. Willis   +15 more
doaj   +1 more source

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