Results 21 to 30 of about 3,157,763 (219)
Cell Reports, 2014 The Wnt/β-catenin pathway and Nanog are key regulators of embryonic stem cell (ESC) pluripotency and the reprogramming of somatic cells. Here, we demonstrate that the repression of Dkk1 by Nanog, which leads indirectly to β-catenin activation, is ...
Lucia Marucci +5 more
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DNA methylation dynamics in the rat EGF gene promoter after partial hepatectomy
Genetics and Molecular Biology, 2014 Epidermal growth factor (EGF), a multifunctional growth factor, is a regulator in a wide variety of physiological processes. EGF plays an important role in the regulation of liver regeneration.
Deming Li +3 more
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Intravital imaging of hair-cell development and regeneration in the zebrafish
Frontiers in Neuroanatomy, 2013 Direct videomicroscopic visualization of organ formation and regeneration in toto is a powerful strategy to study cellular processes that often cannot be replicated in vitro.
Hernan eLopez-Schier +5 more
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ExOrthist: a tool to infer exon orthologies at any evolutionary distance
Genome Biology, 2021 Several bioinformatic tools have been developed for genome-wide identification of orthologous and paralogous genes. However, no corresponding tool allows the detection of exon homology relationships.
Yamile Márquez +7 more
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Topoisomerase 1 cleavage complex enables pattern recognition and inflammation during senescence
Nature Communications, 2020 Here, the authors show that the topoisomerase 1-DNA covalent cleavage complex plays a critical role in mediating cytoplasmic chromatin fragments recognition by cyclic GMP-AMP synthase during senescence.
Bo Zhao +11 more
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Upfront admixing antibodies and EGFR inhibitors preempts sequential treatments in lung cancer models
EMBO Molecular Medicine, 2021 Some antibacterial therapies entail sequential treatments with different antibiotics, but whether this approach is optimal for anti‐cancer tyrosine kinase inhibitors (TKIs) remains open. EGFR mutations identify lung cancer patients who can derive benefit
Ilaria Marrocco +11 more
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A subset of conserved mammalian long non-coding RNAs are fossils of ancestral protein-coding genes
Genome Biology, 2017 Background Only a small portion of human long non-coding RNAs (lncRNAs) appear to be conserved outside of mammals, but the events underlying the birth of new lncRNAs in mammals remain largely unknown.
Hadas Hezroni +5 more
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BMC Pulmonary Medicine, 2019 Background E-cigarette use prevalence has grown rapidly in the US. Despite the popularity of these products, few acute exposure toxicity studies exist, and studies on long-term pulmonary health effects are limited.
Albert D. Osei +8 more
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Phenotyping Diabetes Mellitus on Aggregated Electronic Health Records from Disparate Health Systems
Pharmacoepidemiology, 2023 Background: Identifying patients with diabetes mellitus (DM) is often performed in epidemiological studies using electronic health records (EHR), but currently available algorithms have features that limit their generalizability.
Hui Xing Tan +15 more
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Scientific Reports, 2021 The aim of this study was to assess the effects of irrigation frequency and nitrogen fertilization rate on the abundance, diversity, and composition of soil bacteria in winter wheat.
Haoran Li +5 more
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