To regulate or not to regulate—That is the question [PDF]
Mark Gorney, MD, Napa, CA , is a board-certified plastic surgeon ana an ASAPS member. He serves on the Board of Governors of The Doctors' Company of California, the nation's largest doctor-owned malpractice insurance company. He also serves as chairman of the company's Risk Management Committee and is Consulting Medical Director.
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Regulating the Regulators [PDF]
Regulatory reform is increasingly centred around mechanisms of systematic review processes which ‘regulate the regulators’, These meta-regulatory regimes shift the balance in regulation-making from politicans and parliament to economists in the central agencies of government. The article traces the emergence of a new meta-regulatory regime in Australia
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DNA methylation dynamics in the rat EGF gene promoter after partial hepatectomy
Epidermal growth factor (EGF), a multifunctional growth factor, is a regulator in a wide variety of physiological processes. EGF plays an important role in the regulation of liver regeneration.
Deming Li +3 more
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Intravital imaging of hair-cell development and regeneration in the zebrafish
Direct videomicroscopic visualization of organ formation and regeneration in toto is a powerful strategy to study cellular processes that often cannot be replicated in vitro.
Hernan eLopez-Schier +5 more
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ExOrthist: a tool to infer exon orthologies at any evolutionary distance
Several bioinformatic tools have been developed for genome-wide identification of orthologous and paralogous genes. However, no corresponding tool allows the detection of exon homology relationships.
Yamile Márquez +7 more
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Topoisomerase 1 cleavage complex enables pattern recognition and inflammation during senescence
Here, the authors show that the topoisomerase 1-DNA covalent cleavage complex plays a critical role in mediating cytoplasmic chromatin fragments recognition by cyclic GMP-AMP synthase during senescence.
Bo Zhao +11 more
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Upfront admixing antibodies and EGFR inhibitors preempts sequential treatments in lung cancer models
Some antibacterial therapies entail sequential treatments with different antibiotics, but whether this approach is optimal for anti‐cancer tyrosine kinase inhibitors (TKIs) remains open. EGFR mutations identify lung cancer patients who can derive benefit
Ilaria Marrocco +11 more
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European energy policy : could it be better? [PDF]
This e-booklet gathers some research carried out by FSR Energy since 2010, looking at various topics: from smart grids to Schengen-like energy agreements, and from incentive regulation to European Gas Target Model.
Florence School of Regulation
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A subset of conserved mammalian long non-coding RNAs are fossils of ancestral protein-coding genes
Background Only a small portion of human long non-coding RNAs (lncRNAs) appear to be conserved outside of mammals, but the events underlying the birth of new lncRNAs in mammals remain largely unknown.
Hadas Hezroni +5 more
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Phenotyping Diabetes Mellitus on Aggregated Electronic Health Records from Disparate Health Systems
Background: Identifying patients with diabetes mellitus (DM) is often performed in epidemiological studies using electronic health records (EHR), but currently available algorithms have features that limit their generalizability.
Hui Xing Tan +15 more
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