Results 31 to 40 of about 8,438,047 (360)

Metabolic regulation of gene expression by histone lactylation

open access: yesNature, 2019
The Warburg effect, which originally described increased production of lactate in cancer, is associated with diverse cellular processes such as angiogenesis, hypoxia, polarization of macrophages and activation of T cells.
Di Zhang   +21 more
semanticscholar   +1 more source

TaPYL4, an ABA receptor gene of wheat, positively regulates plant drought adaptation through modulating the osmotic stress-associated processes

open access: yesBMC Plant Biology, 2022
Background Abscisic acid receptors (ABR) involve transduction of the ABA signaling in plants, impacting largely on stress-defensive physiological processes and plant osmotic stress response. In this study, we characterized TaPYL4, a gene of ABR family in
Yanyang Zhang   +6 more
doaj   +1 more source

Investigation of Main Radiation Source above Shield Plug of Unit 3 at Fukushima Daiichi Nuclear Power Station

open access: yesEPJ Web of Conferences, 2017
Pulse height distributions were measured using a CdZnTe detector inside a lead collimator to investigate main source producing high dose rates above the shield plugs of Unit 3 at Fukushima Daiichi Nuclear Power Station.
Hiratama Hideo   +5 more
doaj   +1 more source

Delayed Liver Regeneration after Partial Hepatectomy in Aged Nos2 Knockout Mice

open access: yesCell Journal, 2017
Objective Patients over 60 years of age have higher mortality and morbidity after major liver resections. Nitric oxide (NO) derived from the catalytic activity of Nos2 plays a beneficial role in liver regeneration (LR) after partial hepatectomy (PH). In
Deming Li   +6 more
doaj   +1 more source

To regulate or not to regulate—That is the question [PDF]

open access: yesAesthetic Surgery Journal, 1997
Mark Gorney, MD, Napa, CA , is a board-certified plastic surgeon ana an ASAPS member. He serves on the Board of Governors of The Doctors' Company of California, the nation's largest doctor-owned malpractice insurance company. He also serves as chairman of the company's Risk Management Committee and is Consulting Medical Director.
openaire   +2 more sources

β-Catenin Fluctuates in Mouse ESCs and Is Essential for Nanog-Mediated Reprogramming of Somatic Cells to Pluripotency

open access: yesCell Reports, 2014
The Wnt/β-catenin pathway and Nanog are key regulators of embryonic stem cell (ESC) pluripotency and the reprogramming of somatic cells. Here, we demonstrate that the repression of Dkk1 by Nanog, which leads indirectly to β-catenin activation, is ...
Lucia Marucci   +5 more
doaj   +1 more source

Immunoproteasomes: Regulating the regulator [PDF]

open access: yesProceedings of the National Academy of Sciences, 2005
I f proteins were people, half of the world's population (3 × 109) would cohabit, cheek by jowl, the typically sized vertebrate cell. Proteins are the most abundant macromolecular constituent of cells and certainly the most important and interesting. Because the interactions of proteins with each other and other cellular components are governed by the ...
openaire   +2 more sources

The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation

open access: yesInternational Journal of Molecular Sciences, 2019
The NLRP3 inflammasome is a critical component of the innate immune system that mediates caspase-1 activation and the secretion of proinflammatory cytokines IL-1β/IL-18 in response to microbial infection and cellular damage.
N. Kelley   +3 more
semanticscholar   +1 more source

DNA methylation dynamics in the rat EGF gene promoter after partial hepatectomy

open access: yesGenetics and Molecular Biology, 2014
Epidermal growth factor (EGF), a multifunctional growth factor, is a regulator in a wide variety of physiological processes. EGF plays an important role in the regulation of liver regeneration.
Deming Li   +3 more
doaj   +1 more source

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

open access: yesScience, 2015
Expression, genetic variation, and tissues Human genomes show extensive genetic variation across individuals, but we have only just started documenting the effects of this variation on the regulation of gene expression.
K. Ardlie   +132 more
semanticscholar   +1 more source

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