Results 61 to 70 of about 8,776,825 (339)
MTCH2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cells
Nature Communications, 2018 Reprogramming of mitochondria metabolism occurs during naïve to primed pluripotency differentiation in mouse embryonic stem cells (ESCs). Here the authors show that mitochondrial MTCH2 regulates mitochondrial fusion and that this fusion is required for ...
Amir Bahat +12 more
doaj +1 more source
Reproductive Biology and Endocrinology, 2018 Background LepR tyrosine site mutation mice (Y123F) exhibit decreased serum E2 levels, immature reproductive organs, infertility as well as metabolic abnormalities.
Xiaoyu Tu +6 more
doaj +1 more source
Interaction of external, introjected, and identified regulation with intrinsic motivation in exercise: Relationships with exercise enjoyment [PDF]
, 2005 The present study examined the way in which the exercise-related motives of external regulation, introjected regulation, and identified regulation interacted with intrinsic motivation to relate to exercise enjoyment.
Karageorghis, CI, Vlachopoulos, SP
core
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Multi-locus CRISPRi targeting with a single truncated guide RNA
Nature CommunicationsA critical goal in functional genomics is evaluating which non-coding elements contribute to gene expression, cellular function, and disease. Functional characterization remains a challenge due to the abundance and complexity of candidate elements. Here,
Molly M. Moore +14 more
doaj +1 more source
EPJ Web of Conferences, 2017 Pulse height distributions were measured using a LaBr3 detector set in a 1 cm lead collimator to investigate main radiation source at the operation floor of Fukushima Daiichi Nuclear Power Station Unit 4. It was confirmed that main radiation source above
Hirayama Hideo +4 more
doaj +1 more source
Addressing the Inadequacies of Private Law in the Regulation of Contracts – During and Post Contract Formation Periods [PDF]
, 2011 It has been argued that weaknesses inherent in Private Law rules, which contribute to its inability to effectively regulate contracts, are in part, attributed to its generality as well as inflexibility in adapting to individual situations.
Ojo, Mariane.B.
core +2 more sources
CCT4 promotes tunneling nanotube formation
FEBS Letters, EarlyView.Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto +3 more
wiley +1 more source
Benefits of workplace collaboration with a trauma-informed support service: a qualitative study
BMC Health Services ResearchBackground Trauma-informed services can benefit people involved in a healthcare or legal process by supporting them to engage with systems and minimise risk of retraumatisation.
Jacinta Evans +2 more
doaj +1 more source
Genome Biology, 2021 Background Somatic cell reprogramming is the process that allows differentiated cells to revert to a pluripotent state. In contrast to the extensively studied rewiring of epigenetic and transcriptional programs required for reprogramming, the dynamics of
Claudia Vivori +11 more
doaj +1 more source