Results 81 to 90 of about 8,776,825 (339)

Isoform switching facilitates period control in the Neurospora crassa circadian clock

Molecular Systems Biology, 2008
A striking and defining feature of circadian clocks is the small variation in period over a physiological range of temperatures. This is referred to as temperature compensation, although recent work has suggested that the variation observed is a specific,
Ozgur E Akman, James C W Locke, Sanyi Tang, Isabelle Carré, Andrew J Millar, David A Rand   +5 more
doaj   +1 more source

The long non coding RNAs (lncRNAs) : a new (p)layer in the dark matter.

Frontiers in Genetics, 2012
The transcriptome of a cell is represented by a myriad of different RNA molecules with and without protein-coding capacities. In recent years, advances in sequencing technologies have allowed researchers to more fully appreciate the complexity of whole ...
Thomas eDerrien, Roderic eGuigó, Roderic eGuigó, Rory eJohnson   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Caregiver Behaviors Associated With Emotion Regulation in High-Risk Preschoolers [PDF]

, 2018
Children who witness violence are at risk for developing a range of developmental problems, including deficits in understanding and regulating. The ability to adaptively manage emotions is associated with children’s mental health and their social and ...
Caiozzo, Christina, Grych, John H., Yule, Kristen   +2 more
core   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Regulation of disease signaling by YOD1: potential implications for therapeutic strategies

Cancer Cell International
YOD1 (OTUD2) is a pivotal deubiquitinating enzyme (DUB) of the Otubain family. It plays an essential role in protein degradation and the regulation of cell signal transduction, influencing various biological processes.
Jiawei Zhao, Xiaotong Guo, Houzhong Li, Yujing Chen, Jingjing Du, Juzheng Zhang, Jinfeng Gan, Peitao Wu, Siqi Chen, Xinwen Zhang, Jinfeng Yang, Jiamin Jin   +11 more
doaj   +1 more source

Supporting victim-survivors during investigations of health practitioner misconduct: early learnings from a trauma-informed service

BMJ Open Quality
Objective In 2021, the Australian Health Practitioner Regulation Agency established a support service to provide additional assistance to victim-survivors involved in complaints related to sexual boundary violations. This study evaluates the first stages
sarah anderson, Eva Saar, Jacinta Evans, Katherine Piech   +3 more
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

The effects of the quality of social relationships and emotion regulation ability on the happiness of introvert individuals [PDF]

, 2016
Previous research has shown that extraverts are happier than introverts and, although happy introverts exist, it is unclear under what conditions they can achieve happiness.
Cabello-González, Rosario, Fernández-Berrocal, Pablo, Gutiérrez-Cobo, María José   +2 more
core  

Productivité et mobilité des inventeurs prolifiques : une approche comparative des systèmes d'innovation de quatre grands pays asiatiques (Chine, Corée, Japon, Taiwan) [PDF]

, 2013
In this paper we picture and compare national systems of innovation of four Asian countries (China, Korea, Japan, Taiwan) with some characteristics of their prolific inventors.
Latham, William, Le Bas, Christian, Volodin, Dmitry   +2 more
core   +2 more sources