Results 31 to 40 of about 175,401,209 (303)

Differential timing of gene expression regulation between leptocephali of the two Anguilla eel species in the Sargasso Sea [PDF]

, 2011
The unique life-history characteristics of North Atlantic catadromous eels have long intrigued evolutionary biologists, especially with respect to mechanisms that could explain their persistence as two ecologically very similar but reproductively and ...
Maes, Gregory E., Als, Thomas Damm, Als, Thomas D., Martin Castonguay, Michael M. Hansen, Jérôme St-Cyr, Bernatchez, Louis, Louis Bernatchez, Thomas D. Als, Eric Normandeau, St-Cyr, Jerome, Als, Thomas, Cramb, Gordon, Saint-Cyr, Jérôme, Gordon Cramb, Maes, Gregory, Kalujnaia, S., Hansen, Michael M., Normandeau, Eric, Svetlana Kalujnaia, Hansen, Michael Møller, Kalujnaia, Svetlana, Hansen, Michael, Gregory E. Maes, Castonguay, Martin, Cramb, Gordon; id_orcid   +25 more
core   +1 more source

The role of DDK and Treslin–MTBP in coordinating replication licensing and pre-initiation complex formation

Open Biology, 2021
Treslin/Ticrr is required for the initiation of DNA replication and binds to MTBP (Mdm2 Binding Protein). Here, we show that in Xenopus egg extract, MTBP forms an elongated tetramer with Treslin containing two molecules of each protein.
Ilaria Volpi, Peter J. Gillespie, Gaganmeet Singh Chadha, J. Julian Blow   +3 more
doaj   +1 more source

The human lncRNA LINC-PINT inhibits tumor cell invasion through a highly conserved sequence element

Genome Biology, 2017
Background It is now obvious that the majority of cellular transcripts do not code for proteins, and a significant subset of them are long non-coding RNAs (lncRNAs).
Oskar Marín-Béjar, Aina M. Mas, Jovanna González, Dannys Martinez, Alejandro Athie, Xabier Morales, Mikel Galduroz, Ivan Raimondi, Elena Grossi, Shuling Guo, Ana Rouzaut, Igor Ulitsky, Maite Huarte   +12 more
doaj   +1 more source

A lncRNA-SWI/SNF complex crosstalk controls transcriptional activation at specific promoter regions

Nature Communications, 2020
SWI/SNF complexes regulate chromatin architecture and gene expression. Here the authors report the RNA interactome of SMARCB1-containing SWI/SNF complexes, showing the function of SMARCB1-interacting long noncoding RNA SWINGN in transcriptional ...
Elena Grossi, Ivan Raimondi, Enrique Goñi, Jovanna González, Francesco P. Marchese, Vicente Chapaprieta, José I. Martín-Subero, Shuling Guo, Maite Huarte   +8 more
doaj   +1 more source

Dynamics of Whole-Genome Contacts of Nucleoli in Drosophila Cells Suggests a Role for rDNA Genes in Global Epigenetic Regulation

Cells, 2020
Chromosomes are organized into 3D structures that are important for the regulation of gene expression and differentiation. Important role in formation of inter-chromosome contacts play rDNA clusters that make up nucleoli. In the course of differentiation,
Nickolai A. Tchurikov, Elena S. Klushevskaya, Daria M. Fedoseeva, Ildar R. Alembekov, Galina I. Kravatskaya, Vladimir R. Chechetkin, Yuri V. Kravatsky, Olga V. Kretova   +7 more
doaj   +1 more source

Wigwams : identifying gene modules co-regulated across multiple biological conditions [PDF]

, 2014
Motivation: Identification of modules of co-regulated genes is a crucial first step towards dissecting the regulatory circuitry underlying biological processes. Co-regulated genes are likely to reveal themselves by showing tight co-expression, e.g.
Rhodes, Johanna, Jenkins, Dafyd J, Jironkin, Aleksey, Kiddle, Steven J., Beynon, Jim, Buchanan-Wollaston, Vicky, Kiddle, Steven J, Hills, Claire E., Denby, Katherine J, Denby, Katherine J., Hill, Claire, Jenkins, Dafyd J., Zhang, Peijun, Polański, Krzysztof, Kiddle, Steven, Ott, Sascha, Rhodes, Johanna; id_orcid   +16 more
core   +1 more source

Gene expression regulation in allopolyploid fish [PDF]

, 2019
Plants, invertebrates and even lower vertebrates are known to deal with hybridization and polyploidy very successfully, surpassing the genetic constrains those phenomena bring.
Matos, Isa
core   +1 more source

Comparative genetic, proteomic and phosphoproteomic analysis of C. elegans embryos with a focus on ham-1/STOX and pig-1/MELK in dopaminergic neuron development

Scientific Reports, 2017
Asymmetric cell divisions are required for cellular diversity and defects can lead to altered daughter cell fates and numbers. In a genetic screen for C.
Sarah-Lena Offenburger, Dalila Bensaddek, Alejandro Brenes Murillo, Angus I. Lamond, Anton Gartner   +4 more
doaj   +1 more source

Efficient and Rapid Analysis of Polysomes and Ribosomal Subunits in Cells and Tissues Using Ribo Mega-SEC

Bio-Protocol, 2021
Polysome profile analysis is a popular method for separating polysomes and ribosomal subunits and is typically achieved using a sucrose density gradient (SDG).
Harunori Yoshikawa, Ramasubramanian Sundaramoorthy, Daniel Mariyappa, Hao Jiang, Angus Lamond   +4 more
doaj   +1 more source

Association of uncoupling protein (Ucp) gene polymorphisms with cardiometabolic diseases

Molecular Medicine, 2020
The hereditary aspect of obesity is a major focus of modern medical genetics. The genetic background is known to determine a higher-than-average prevalence of obesity in certain regions, like Oceania.
Anna E. Pravednikova, Sergey Y. Shevchenko, Victor V. Kerchev, Manana R. Skhirtladze, Svetlana N. Larina, Zaur M. Kachaev, Alexander D. Egorov, Yulii V. Shidlovskii   +7 more
doaj   +1 more source