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Transcriptome Dynamics of BmN Cells During the Early Phase of Bombyx mori Nucleopolyhedrovirus Infection. [PDF]
Wang X, Miao F, Wang W, Sun J, Yao L.
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Autophagy and ubiquitination in important swine viral infections: Host defense and viral antagonism. [PDF]
He Z, Liu M, Xie Q, Lu H, Guo C.
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MicroRNA regulation of viral replication in teleost fish: a review
Reviews in Aquaculture, 2021AbstractMicroRNAs (miRNAs) are single‐stranded non‐coding RNA molecules. In addition to participating in various biological processes of eukaryotes, such as cell proliferation, development, differentiation, metabolism, tumorigenesis, and apoptosis, miRNAs also play an important role in the regulation of virus replication.
Chi Zhang, Jiagang Tu, Yong‐An Zhang
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Molecular mechanisms of
AbstractLipid phosphoinositides are master signaling molecules in eukaryotic cells and key markers of organelle identity. Because of these important roles, the kinases and phosphatases that generate phosphoinositides must be tightly regulated. Viruses can manipulate this regulation, with the Type III phosphatidylinositol 4‐kinases (PI4KA and PI4KB ...
Jacob A. McPhail, John E. Burke
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Ebola virus replication is regulated by the phosphorylation of viral protein VP35
Biochemical and Biophysical Research Communications, 2020Ebola virus (EBOV) is a zoonotic pathogen, the infection often results in severe, potentially fatal, systematic disease in human and nonhuman primates. VP35, an essential viral RNA-dependent RNA polymerase cofactor, is indispensable for Ebola viral replication and host innate immune escape.
Lin, Zhu +14 more
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SSRN Electronic Journal, 2022
p53 exerts its tumour suppressor activity by modulating hundreds of genes and it can also repress viral replication. Such is the case of human papillomavirus (HPV) through targeting the E2 master regulator, but the biochemical mechanism is not known.
Borkosky, Silvia Susana +8 more
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p53 exerts its tumour suppressor activity by modulating hundreds of genes and it can also repress viral replication. Such is the case of human papillomavirus (HPV) through targeting the E2 master regulator, but the biochemical mechanism is not known.
Borkosky, Silvia Susana +8 more
openaire +3 more sources
HTLV-1-encoded p30II is a post-transcriptional negative regulator of viral replication
Nature Medicine, 2004Human T-cell leukemia/lymphoma virus type 1 (HTLV-1) persists despite a vigorous virus-specific host immune response, and causes adult T-cell leukemia and lymphoma in approximately 2% of infected individuals. Here we report that HTLV-1 has evolved a genetic function to restrict its own replication by a novel post-transcriptional mechanism.
Christophe, Nicot +9 more
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Antiviral Research, 1994
The mechanisms which regulate the replication of lactate dehydrogenase-elevating virus (LDV), a persistent murine model virus which infects macrophages, are unclear. For this study, the effects of murine recombinant interferon-gamma (IFN-gamma) and tumor necrosis factor-alpha (TNF-alpha) on LDV replication were examined.
W A, Cafruny +3 more
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The mechanisms which regulate the replication of lactate dehydrogenase-elevating virus (LDV), a persistent murine model virus which infects macrophages, are unclear. For this study, the effects of murine recombinant interferon-gamma (IFN-gamma) and tumor necrosis factor-alpha (TNF-alpha) on LDV replication were examined.
W A, Cafruny +3 more
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Regulation of apoptosis and replicative senescence in CD8+ T cell following acute viral infection
Apoptosis, 2000Viral infections are characterised by a large expansion of CD8+ effector T cells. Once generated, these T cells must be cleared and homeostasis re-established. In this review we describe two mechanisms, apoptosis and replicative senescence which are thought to play a vital role in this process.
F J, Plunkett +3 more
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MicroRNAs in HIV infection: dual regulators of viral replication and host immunity
Naunyn-Schmiedeberg's Archives of PharmacologyMicroRNAs (miRNAs) are small non-coding RNAs that play a crucial role in regulating gene expression by binding to target messenger RNAs (mRNAs), leading to their degradation or translational repression. Over the past few years, significant progress has been made in understanding the role of miRNAs in various biological processes, including viral ...
Reda M. Mansour +12 more
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