Results 91 to 100 of about 1,302,388 (314)

International Competitiveness and Environmental Regulations [PDF]

open access: yes
This study follows the standard factor endowment approach to explain the effects of environmental regulations on net exports in different product-based industries.
Babool, Md. Ashfaqul Islam   +1 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

THE PREDICTION OF SCIENTIFIC-TECHNOLOGICAL DEVELOPMENT OF GRAIN ECONOMY OF THE RUSSIAN FEDERATION

open access: yesЗерновое хозяйство России, 2018
The article deals with the results of predictions of scientific-technological development of grain economy of the Russian Federation. The results of the study determined that the efficient use of land resources under grain crops could be achieved if the ...
A. N. Tarasov
doaj   +2 more sources

Cytokinin elevation caused by high light intensity contributes substantially to the increase of thermotolerance of rice plants

open access: yesPlant Stress
Light is a crucial factor affecting plant development. Rice (Oryza sativa) responses to high light (HL, 1300 μmol m−2 s−1, 27 °C) were characterized.
Sylva Prerostova   +9 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Regulations and robust low-carbon buildings [PDF]

open access: yes, 2009
Building regulations and associated calculation methods have been rapidly evolving, driven in Europe by the European Union Energy Performance of Buildings Directive. As an example, the current UK regulations are explored in relation to buildings that are
Tuohy, Paul
core   +1 more source

Tobacco Cessation Clinic

open access: yesTobacco Prevention and Cessation, 2019
Pakistan has the high prevalence of cigarette smoking (15.6 million) among top 10 countries in the world. Tobacco kills 160,000 every year, 5000 admitted to hospital every day, children between 6 to 15 age start smoking every day.
Qamar Goraya
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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