Results 121 to 130 of about 3,451,628 (312)
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Assessing the impact of amended building regulations on the operations of UK construction companies [PDF]
, 2008 The UK government continues to make regular amendments to building regulations. This is in order to keep these regulations relevant to today’s prevailing construction environment. More recently, UK building regulations have been amended to facilitate the
Dawson, Richard +2 more
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Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
GOVERNMENTAL SUPPORT OF GRAIN MARKET IN RUSSIA
Зерновое хозяйство России, 2018 Grain production is historically a basis of stable functioning of agricultural sector, it has a system forming function for other branches of economy, it determines the level of food security for population and is a specific indicator of economic welfare
I. V. Baranova, E. S. Shevkunova
doaj +2 more sources
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
ENVIRONMENTAL REGULATIONS AND COMPETITIVENESS [PDF]
Costs of environmental regulations, although relatively small, can be critical in the competitiveness of a product since the cost advantages of producers in one country are often very slim.
Colyer, Dale
core +1 more source
Visiting Rules and Regulations: A Preliminary Study [PDF]
, 1988 A revised version of this paper was published as: Schafer, N.E. (1989). "Prison Visiting: Is It Time to Review the Rules?" Federal Probation 53(4): 25–30 (Dec 1989).
Schafer, N. E.
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Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source