Results 121 to 130 of about 1,609,140 (304)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Staff Rules and Regulations [PDF]

, 1965
Staff Rules and Regulations, Addis Ababa, March 1965It consists rules and regulations which should be applicable to all statutory members of the secretariat.
Organization of African Unity
core  

The development of Ottoman urban regulations: Istanbul, 1700-1900

, 2017
This study focuses on the formation of urban regulations in the Ottoman State between 1700-1900, analyzing the eighteenth century as a preparatory period for the systematic approach of the nineteenth century.
Çokuğraş, I., İrem Gençer, C.
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Regulations and Requirements

, 2012
Summary This chapter contains sections titled: Background Information Existing Regulations and Standards Sense and Avoid Requirements Human Factors and Situational Awareness Considerations Conclusions Acknowledgments ...
Delgado, L., Prats, X., Ramírez, J., Royo, P.   +3 more
core   +1 more source

Barriers to neurosurgical care in Gaza: navigating health system disruptions and scarcity of resources

Egyptian Journal of Neurosurgery
The ongoing conflict in Gaza has severely impacted the healthcare system, particularly in neurosurgery. Patients face significant challenges in accessing timely medical care due to movement restrictions, destruction of infrastructure, and a lack of ...
Muhammad Aashir Aftab, Eesha Yaqoob, Saad Javed, Bipin Chaurasia   +3 more
doaj   +1 more source

Phytochemical Profiling and Antimicrobial Properties of Various Sweet Potato (Ipomoea batatas L.) Leaves Assessed by RP-HPLC-DAD

Foods
This study aimed to investigate the leaves of six cultivars of Ipomoea batatas L. from the USA, focusing on their Total Polyphenol Content (TPC), Total Flavonoid Content (TFC), antioxidant, and antimicrobial activities.
Tasbida Sultana, Shahidul Islam, Muhammad Abul Kalam Azad, Md Jahurul Haque Akanda, Atikur Rahman, Md Sahidur Rahman   +5 more
doaj   +1 more source

Regulating the regulators

Journal of Experimental Medicine, 2009
Co-culture of PD-L1–expressing beads (red) and naive T cells (purple) promotes their conversion into T reg cells (green).
openaire   +2 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source