Results 31 to 40 of about 1,296,155 (314)

Heat Acclimation and Inhibition of Cytokinin Degradation Positively Affect Heat Stress Tolerance of Arabidopsis

Frontiers in Plant Science, 2020
In order to pinpoint phytohormone changes associated with enhanced heat stress tolerance, the complex phytohormone profiles [cytokinins, auxin, abscisic acid (ABA), jasmonic acid (JA), salicylic acid and ethylene precursor 1-aminocyclopropane-1 ...
Sylva Prerostova, Petre I. Dobrev, Barbara Kramna, Alena Gaudinova, Vojtech Knirsch, Lukas Spichal, Marek Zatloukal, Radomira Vankova   +7 more
doaj   +1 more source

ER-Localized PIN Carriers: Regulators of Intracellular Auxin Homeostasis

Plants, 2020
The proper distribution of the hormone auxin is essential for plant development. It is channeled by auxin efflux carriers of the PIN family, typically asymmetrically located on the plasma membrane (PM).
Nayyer Abdollahi Sisi, Kamil Růžička
doaj   +1 more source

Improved wind-driven optimization algorithm for the optimization of hydropower generation from a reservoir

Journal of Hydroinformatics, 2021
The improvement of reservoir operation optimization (ROO) can lead to comprehensive economic benefits as well as sustainable development of water resources. To achieve this goal, an algorithm named wind-driven optimization (WDO) is first employed for ROO
Yin Liu, Shuanghu Zhang, Yunzhong Jiang, Dan Wang, Qihao Gu, Zhongbo Zhang   +5 more
doaj   +1 more source

COVID 19 Pandemic & Pakistan; Limitations and Gaps

Global Biosecurity, 2020
: Background: The 2019 novel coronavirus disease (COVID-19) has spread to more than 213 countries and as of 17th April 2020, 1995,983 confirmed cases and 131,037 deaths have been reported globally.
Nadia Noreen, Saima Dil, Saeed Ullah Khan Niazi, Irum Naveed, Naveed Ullah Khan, Farida Khudaid Khan, Shehla Tabbasum, Deepak Kumar   +7 more
doaj   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Evidence that tyrosine hydroxylase does not have enzymatic activity in neurons of the supraoptic nucleus

Frontiers in Endocrinology
IntroductionAlthough numerous neurons expressing tyrosine hydroxylase (TH), the first enzyme of catecholamine synthesis, were discovered in the supraoptic nucleus (SON) of hypothalamus in animals almost forty years ago, mainly under osmotic stress, the ...
Tatiana S. Pronina, Dmitry V. Troshev, Anna A. Kolacheva, Vsevolod V. Bogdanov, Michael V. Ugrumov   +4 more
doaj   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Hallmarks of nuclear metabolism: implications for genome integrity, nuclear signaling, and therapeutic targeting

npj Metabolic Health and Disease
Certain metabolic enzymes localize to the nucleus, where they perform regulatory functions that extend far beyond canonical metabolism. Once inside, they influence chromatin organization, transcription, DNA repair, and cell cycle progression. This review
Alisa Schmidt, Matilda Pfeiffer, Sara Sdelci   +2 more
doaj   +1 more source