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TOX is a critical regulator of tumour-specific T cell differentiation

open access: yesNature, 2019
Tumour-specific CD8 T cell dysfunction is a differentiation state that is distinct from the functional effector or memory T cell states1–6. Here we identify the nuclear factor TOX as a crucial regulator of the differentiation of tumour-specific T (TST ...
Andrew C Scott   +2 more
exaly   +2 more sources
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ERK signalling: a master regulator of cell behaviour, life and fate

Nature Reviews Molecular Cell Biology, 2020
Hugo Lavoie, Marc Therrien
exaly   +2 more sources

TGF-β: the master regulator of fibrosis

Nature Reviews Nephrology, 2016
Xiao-ming Meng   +2 more
exaly   +2 more sources

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