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Regulating the Regulators

Science, 2007
Growth factors and nutrients, particularly amino acids, regulate cell growth and proliferation in part through the serine-threonine protein kinase mTOR (mammalian target of rapamycin). Activity of mTOR is regulated through the small guanosine triphosphatase Rheb (Ras homolog enriched in brain). Bai et al .
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SIRTUIN 1: Regulating the regulator

Biochemical and Biophysical Research Communications, 2008
Earlier analyses on the sirtuin family of histone deacetylases and its well-known member SIRT1 had their primary focus mostly on the identification of cellular targets exploring molecular mechanisms and functional networks in the control of metabolic homeostasis, differentiation, apoptosis and cell survival.
Barbara, Zschoernig, Ulrich, Mahlknecht
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Regulating the Regulator

Science, 1999
Major histocompatibility complex (MHC) class II antigens are almost exclusively expressed on immune cells such as dendritic cells and activated macrophages. It is known that their expression is necessary for the activation of lymphocytes and for a healthy immune response.
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Regulating the Regulator

Science's STKE, 2006
MicroRNAs (miRNAs) have emerged as posttranscriptional regulators of gene expression that appear to have important roles in complex processes like development and the development of cancer. Although the abundance of miRNAs increases dramatically during development and is decreased in some cancer cells, how the production of miRNAs is ...
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Regulating the Regulators

The University of Chicago Law Review, 1996
Since the 1970s, there has been a tremendous growth in government regulation pertaining to risk and the environment. These efforts have emerged quite legitimately because market processes alone cannot fully address risk-related concerns.' Without some kind of regulation or liability, for example, firms lack appropriate incentives to restrict their ...
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The explicit linear quadratic regulator for constrained systems

at - Automatisierungstechnik, 2003
A. Bemporad   +3 more
semanticscholar   +1 more source

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

Nature, 1999
Y. Kong   +16 more
semanticscholar   +1 more source

On regulating regulation

European Journal of Clinical Pharmacology, 1981
I, Lunde, M N, Dukes
openaire   +2 more sources

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