Results 61 to 70 of about 1,314,428 (309)
Active regulator of SIRT1 is required for cancer cell survival but not for SIRT1 activity [PDF]
, 2013 The NAD+-dependent deacetylase SIRT1 is involved in diverse cellular processes, and has also been linked with multiple disease states. Among these, SIRT1 expression negatively correlates with cancer survival in both laboratory and clinical studies ...
Knight, J.R.P. +5 more
core +1 more source
Agronomy, 2019 Mechanical harvesting has become inevitable for cotton production in China due to the rising labor cost in the country. It usually requires a moderate plant height and compact plant architecture.
Wei Yan +13 more
doaj +1 more source
“Emotional regulation” or “affective regulation”?
Frontiers in PsychologyIn recent decades, there has been an increased interest in psychology to understand the emotional experience. This growing interest has led to a proliferation of terms, among which regulation, intelligence, and emotional competence stand out. Research in these areas has facilitated a better understanding of what emotion entails and how to intervene in ...
De Jesús Gómez, Ruth +1 more
openaire +4 more sources
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Factor equivalence of Galois modules and regulator constants [PDF]
, 2013 We compare two approaches to the study of Galois module structures: on the one hand, factor equivalence, a technique that has been used by Fröhlich and others to investigate the Galois module structure of rings of integers of number fields and of their ...
Bartel, Alex, Alex Bartel
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Le modèle de la société de l’information au Royaume-Uni et en Écosse
Netcom, 2007 As soon as he came to power, Tony Blair linked the challenge of information and communication technologies to state and public services reforms, and placed the central state at the heart of a British-style information society.
Lise-Marie Couronne-Geary
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Corporate law in Spain: some modern trends in the development of companies
Ибероамериканские тетради, 2018 The article examines modern interpretations of the corporate law, taking into account the example of Spain. The current trends in the activities of the companies are analyzed, special attention is focused on the elaboration of codes of good governance of
Elena Orlova
doaj +1 more source