Results 41 to 50 of about 6,034,940 (339)
Taking regulatory action [PDF]
, 2011 "This document sets out the approach we intend to follow in exercising our statutory powers to take regulatory action. It is consistent with the Act in its description of our powers, the way in which we will exercise them, and the matters to which we ...
core
The evolution of complex gene regulation by low specificity binding sites
, 2012 Transcription factor binding sites vary in their specificity, both within and between species. Binding specificity has a strong impact on the evolution of gene expression, because it determines how easily regulatory interactions are gained and lost ...
Plotkin, Joshua B. +1 more
core +1 more source
The Diffusion of Regulatory Oversight [PDF]
, 2013 The idea of cost-benefit analysis has been spreading internationally for centuries — at least since an American named Benjamin Franklin wrote a letter in 1772 to his British friend, Joseph Priestley, recommending that Priestley weigh the pros and cons of
Wiener, Jonathan B.
core +2 more sources
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic kidney disease is a growing public health problem worldwide, and the number of patients requiring renal replacement therapy is steadily increasing. Türkiye has experienced a similar rise in both the incidence and prevalence of renal replacement therapy over the past decades; however, national‐level projections of future ...
Arzu Akgül +2 more
wiley +1 more source
Land use, environmental change, and sustainable development: The role of institutional diagnostics
International Journal of the Commons, 2011 Although the “tragedy of the commons” is common currency in popular accounts of problems arising in human-environment relations, empirical research has shown that common-property systems do not always lead to tragic outcomes. Moreover, systems of private
Oran Young
doaj +1 more source
International Psychogeriatrics, 2003 Any medical decision generates consequences for the patient and for society. Medical practice should, therefore, be performed under the guidance of the following ethical principles: beneficence, nonmaleficence, autonomy, justice, integrity, dignity, and vulnerability.
José L, Molinuevo, Rafael, Blesa
openaire +2 more sources
Regulatory mechanisms of PD-1/PD-L1 in cancers
Molecular CancerImmune evasion contributes to cancer growth and progression. Cancer cells have the ability to activate different immune checkpoint pathways that harbor immunosuppressive functions.
Xin Lin +7 more
semanticscholar +1 more source
An update on the regulatory mechanisms of NLRP3 inflammasome activation
Cellular & Molecular Immunology, 2021 The NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inflammasome is a multiprotein complex involved in the release of mature interleukin-1β and triggering of pyroptosis, which is of paramount importance in a variety of physiological and ...
Seungwha Paik +4 more
semanticscholar +1 more source
Gene regulatory network subcircuit controlling a dynamic spatial pattern of signaling in the sea urchin embryo [PDF]
, 2008 We dissect the transcriptional regulatory relationships coordinating the dynamic expression patterns of two signaling genes, wnt8 and delta, which are central to specification of the sea urchin embryo endomesoderm.
Alifragis +34 more
core +3 more sources
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source