Results 51 to 60 of about 6,034,940 (339)

Boolean network model predicts cell cycle sequence of fission yeast [PDF]

, 2007
A Boolean network model of the cell-cycle regulatory network of fission yeast (Schizosaccharomyces Pombe) is constructed solely on the basis of the known biochemical interaction topology.
A Faure, A Sveiczer, B Novak, B Novak, C Espinosa-Soto, C Martin-Castellanos, DT Gillespie, DT Gillespie, F Li, Gustavo Stolovitzky, J Correabordes, J Hasty, JJ Tyson, JJ Tyson, JJ Tyson, K Lundgren, KC Gunsalus, KE Thum, L Glass, L Mendoza, L Sanchez, Maria I. Davidich, NAW Riel, P Russel, P Smolen, R Albert, R Visintin, S Bornholdt, S Braunewell, S Jaspersen, S Li, S Trautmann, S Yamaguchi, SA Kauffman, SA Kauffmann, SL Forsburg, Stefan Bornholdt, U Alon, V Batagelj, V Buck, V Simanis   +40 more
core   +5 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Home nursing in clinical trials: Result from semi-structured qualitative interviews

Perspectives in Clinical Research
There is a need to transition from conventional (on-site) clinical trials (CTs) to trials conducted within the comfort of a patient’s home or community (decentralized CT) through e-consent, remote data monitoring, and telemedicine consults. This shift in
Pooja Sharma, Subhrojyoti Bhowmick, Kedar Nayak, Soma Bhattacharjee, Sandeep Lahiry   +4 more
doaj   +1 more source

Expanding regulatory science: Regulatory complementarity and reliance

Clinical and Translational Science, 2023
AbstractDrug regulatory institutions, infrastructures, and systems are becoming increasingly interconnected across national boundaries and increasingly global in outlook. This process is reflected in the broadening and deepening application of the principles and practice of Regulatory Reliance, and parallel initiatives to strengthen the capacities of ...
Jackson K. Mukonzo, Helen Byomire Ndagije, George Tsey Sabblah, Wangui Mathenge, David A. Price, Thaddeus H. Grasela   +5 more
openaire   +3 more sources

Harmonising Basel III and the Dodd Frank Act through International Accounting Standards – Reasons why International Accounting Standards Should Serve as “Thermostats [PDF]

, 2012
Why should differences between regulatory and accounting policies be mitigated? Because mitigating such differences could facilitate convergence – as well as financial stability. The paper ―Fair Value Accounting and Procyclicality: Mitigating Regulatory
Ojo, Mariane.B.
core   +3 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Evaluation of CD4+ CD25+/high CD127low/- Regulatory T-Cells in Different Stages of Psoriatic Arthritis Patients

Advanced Biomedical Research
Background: Psoriatic arthritis (PsA) is a systemic auto-immune condition characterized by diverse and distinctive inflammation, affecting both musculoskeletal and extra-articular systems.
Roya Safari, Abdolhussein Shakurnia, Ata Ghadiri, Elham Rajaei, Karim Mowla, Maryam Haidari   +5 more
doaj   +1 more source

Extemporaneous Compounding Practice for Dermatologic Preparations in Ethiopian Public Hospitals: Regulatory Requirements and Quality Concerns

Risk Management and Healthcare Policy, 2021
Muluken Nigatu Selam,1 Andualem Ababu2 1Department of Pharmaceutics and Social Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia; 2Pharmaceutical and Medical Equipment Directorate (PMED), Ministry of ...
Selam MN, Ababu A
doaj  

Exploring the Application of Micellar Drug Delivery Systems in Cancer Nanomedicine

Pharmaceuticals, 2023
Various formulations of polymeric micelles, tiny spherical structures made of polymeric materials, are currently being investigated in preclinical and clinical settings for their potential as nanomedicines.
Qi Wang, Keerthi Atluri, Amit K. Tiwari, R. Jayachandra Babu   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source