Results 61 to 70 of about 6,140,187 (206)

Targeting GPR68 Alleviates Inflammation and Lipid Accumulation in Metabolic Dysfunction-Associated Steatohepatitis

open access: yesBiology
Metabolic dysfunction-associated steatohepatitis (MASH) is a prevalent chronic liver disease characterized by hepatocellular injury, inflammation, and lipid accumulation, for which effective pharmacotherapies remain limited.
Jianlei Wei   +3 more
doaj   +1 more source

Ten Things You Need to Know about Regulation and Never Wanted to Ask [PDF]

open access: yes
For most people, “to regulate” means to control or direct others by rules, standards or principles. The term can carry negative baggage, particularly when attached to government. Rightly or wrongly, government regulation on occasion connotes authority
Braithwaite, Valerie   +1 more
core  

Homeostasis in gene regulatory networks

open access: yesInternational Journal of Biomathematics
Gene regulatory networks lie at the heart of many important intracellular signal transduction processes. A Gene Regulatory Network (GRN) is abstractly defined as a directed graph, where the nodes represent genes and the edges represent the causal regulatory interactions between genes. It can be used to construct mathematical models describing the time-
Fernando Antoneli   +3 more
openaire   +2 more sources

-methyladenosine (mA)-circHECA from secondary hair follicle of cashmere goats: identification, regulatory network and expression regulated potentially by methylation of its host gene promoter [PDF]

open access: yesAnimal Bioscience
Objective The objective of this study was to identify the N6-methyladenosine (m6A)-circHECA molecule in secondary hair follicles (SHFs) of cashmere goats, and generate its potential regulatory network, as well as explore the potential relationship ...
Jincheng Shen   +10 more
doaj   +1 more source

Fear-themed digital media exposure and sleep regulatory sensitivity in school-aged children: preliminary observations toward a developmental PhenoSleep construct

open access: yesFrontiers in Neurology
IntroductionFear-themed digital media exposure is increasingly common in school-aged children, yet its developmental implications remain insufficiently understood.
Martina Gnazzo   +23 more
doaj   +1 more source

The One that Got Away: Detecting Non-compliance in order to Ensure Voluntary Compliance [PDF]

open access: yes
Based on responsive regulation, the Australian Taxation Office (ATO) compliance model was developed as a way of dealing with the complexities of the Australian tax system. The title of this article ‘The one that got away’ refers both to the job of ATO
Australian National University. Regulatory Institutions Network   +1 more
core  

Mining the genome and regulatory networks.

open access: yesGenome biology, 2006
A report on the 16th International Conference on Genome Informatics (GIW 2005), Yokohama, Japan, 19-21 December 2005.
Potapov, Anatolij P., Wingender, Edgar
openaire   +3 more sources

The stem of Schisandra chinensis and Schisandrin B alleviated DNCB-induced atopic dermatitis in mice by inhibiting the NF-κB pathway

open access: yesFrontiers in Immunology
BackgroundAtopic dermatitis (AD) is a chronic, pruritic, inflammatory skin disorder. While the stem of Schisandra chinensis has been extensively studied for its pharmacological properties, including anti-inflammatory, antioxidant, and hepatoprotective ...
Cai Ye   +10 more
doaj   +1 more source

Shame, ethical identity and conformity: Lessons from research on the psychology of social influence [PDF]

open access: yes
Understanding emotion is essential to developing an account of why people commit crime and how they react when caught. Research across a number of disciplines suggests that shame, which is the focus of this chapter, plays a significant role in how ...
Harris, Nathan   +1 more
core  

Frontiers and Perspectives of Artificial Intelligence in Forensic Research on CT Imaging Diagnosis of Rib Fractures

open access: yesFayixue Zazhi
Rib fractures are relatively common in thoracic trauma, and the number of fractured ribs as well as the presence of malunion are closely associated with criminal sentencing and civil compensation, thereby holding significant forensic significance.
SUN Ya-ning   +9 more
doaj   +1 more source

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