Results 91 to 100 of about 1,617,487 (313)
Regulatory instruments and their effects on investment behavior [PDF]
Regulatory instruments have long been understood to have a powerful effect on investment, and part of the motivation for introducing higher-powered regulatory regimes and contracts was to reduce incentives for inefficiency and over-investment (gold ...
Burns, Phil, Riechmann, Christoph
core
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Regulatory Issues for Genetic Testing in Clinical Practice [PDF]
Molecular Biotechnology, 2008 Whereas deliver of health care is nationally based with great differences in ways of service provision and financing between countries, and thus not subject to international regulations, genetic testing has become more exposed to international regulations and conventions.
openaire +2 more sources
Efficiency and Productivity Analysis in Regulation and Governance [PDF]
This paper surveys the application of efficiency and productivity analysis to recent regulatory experience, especially in Europe. From a review of regulatory case studies, particularly of network industries, it is clear that regulatory practice differs ...
Thomas Weyman-Jones
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Do Regulatory and Curriculum Requirements for Interprofessional Practice Align?
Journal of Multidisciplinary Healthcare, 2023 Sharon Brownie,1– 3 Ema Tokolahi,4 Patrick Broman,3 Marrin Haggie,3 Patrea Andersen3,5,6 1School of Health Sciences, Swinburne University of Technology, Melbourne, VIC, Australia; 2School of Health Sciences and Social Work, Griffith University, Gold ...
Brownie S +4 more
doaj
Benchmarking and Regulation in the Electricity Distribution Sector [PDF]
In the last two decades electricity distribution sector have witnessed a wave of regulatory reforms aimed at improving efficiency through incentive regulation.
Aurelio Fetz +2 more
core
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source