Results 141 to 150 of about 29,276,589 (300)
This compilation is the annual cumulation of bibliographic data and abstracts for the formal regulatory and technical reports issued by the U.S.
Sheehan, M.A.
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
State of Connecticut Public Utilities Regulatory Authority; Public Utilities Regulatory Authority
Updated irregularly; Began in 2011.; Title from home page (publisher's Web site, viewed July 6, 2011).; At head of title: State of Connecticut.; Harvested from the web on 7/7/11Official website of the Connecticut Public Utilities Regulatory Authority ...
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This document is a planning guide for those Federal agencies that work with the Nuclear Regulatory commission (NRC) during the initial hours of response to a serious radiological emergency in which the NRC is the Lead Federal Agency (LFA).
R Hogan, Hogan, R. T.
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Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
U.S. Nuclear Regulatory Commission accountability report, fiscal year 1995. Volume 1
The US Nuclear Regulatory Commission (NRC) is one of six Federal agencies participating in a pilot project to streamline financial management reporting.
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Health Products Regulatory Authority Conflicts of Interest Policy
Given the nature of the HPRA’s regulatory functions, particular care and transparency is necessary in relation to potential conflicts of interest in relation to the industries regulated by the HPRA.
Health Products Regulatory Authority (HPRA)
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