Results 271 to 280 of about 2,009,353 (358)

CXCL16 Producing Tumor Clones Are Shaping Immunosuppressive Microenvironment in Squamous Cell Carcinoma via CXCR6 Regulatory T Cell. [PDF]

Cancer Med
Choi HS, Jung S, Kim KM, Lee M, Park JH, Hwang S, Cha SM, Young JN, Poplausky D, Nam H, Gulati N, Park CG, Kim HJ, Park JU.   +13 more
europepmc   +1 more source

T-regulatory-1 (TR1) cells prevent colitis induced by enteric bacterial antigen-reactive pathogenic TH1 cells

, 2000
Yingzi Cong, Casey T. Weaver, Audrey J. Lazenby, John P. Sundberg, Charles O. Elson   +4 more
openalex   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

The molecular mechanisms for regulatory T cell immunosuppression

Frontiers in Immunology, 2012
Kendall A Smith
doaj   +1 more source

Gut Microbiota-Butyrate-PPARγ Axis Modulates Adipose Regulatory T Cell Population. [PDF]

Adv Sci (Weinh)
Chen B, Guan L, Wu C, Gong Y, Wu L, Zhang M, Cao Z, Chen Y, Yang C, Wang B, Li Y, Li B, Bi Y, Ning G, Wang J, Wang W, Liu R.   +16 more
europepmc   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Transient regulatory T cell manipulation is limited by anti-antibody responses in HIV-1 envelope immunized rhesus macaques. [PDF]

iScience
Gu S, Luo K, Von Holle TA, Gurley TC, Bouton-Verville H, Sutherland LL, Parks R, Shen X, Spreng RL, Tomaras GD, Montefiori DC, Liao HX, Haynes BF, Moody MA.   +13 more
europepmc   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Dysfunctional glycolysis-UCP2-fatty acid oxidation promotes CTLA4^intFOXP3^int regulatory T-cell production in rheumatoid arthritis. [PDF]

Mol Med
Han J, Zhou Z, Wang H, Chen Y, Li W, Dai M, Bian J, Zhao E, He J, Zhang X, Yi H, Shao L.   +11 more
europepmc   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source