Results 1 to 10 of about 99,561 (267)
Immunomodulatory Effect of Propolis on Foxp3 Gene Expression in Human Peripheral Blood Mononuclear Cells Stimulated in vitro with Pseudomonas Aeruginosa Ag [PDF]
Archives of Razi Institute, 2021 Immune balance during infection is critical for both supporting the defense of the immune system of the body and preventing an overly aggressive immune response.
F. A Alwaeely, K. N Madlum, M. A Alsaadi
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Upregulation of Cytotoxic T-Lymphocyte-Associated Protein 4 and Forkhead Box P3 Transcripts in Peripheral Blood of Patients with Bladder Cancer [PDF]
Iranian Journal of Medical Sciences, 2021 Background: Regulatory T cells (Tregs) play a key role in the progression of tumors. These cells express forkhead box P3 (FOXP3) and cytotoxic T-lymphocyte-associated protein 4 (CTLA4), which are the potential targets for cancer immunotherapy.
Ali Ariafar +7 more
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FOXP3 expression in FOXP3+ tumor cells promotes hepatocellular cells metastasis [PDF]
Translational Cancer Research, 2020 Forkhead transcription factor 3 (FOXP3) is a key molecule for the development of regulatory T cell. Recent studies showed that FOXP3 was also expressed in tumor cells. This study is designed to identify the expression of FOXP3 and its pathogenesis in hepatocellular carcinoma (HCC).Through immunohistochemistry, RNA extraction and Real-Time Quantitative ...
Zhang, Henghui +9 more
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Human Vaccines & Immunotherapeutics, 2022 Autoimmune diseases are caused when immune cells act against self-protein. This biological self–non-self-discrimination phenomenon is controlled by a distinct group of lymphocytes known as regulatory T cells (Tregs), which are key inflammatory response ...
Tapas Kumar Goswami +9 more
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Characterization of human epithelial resident memory regulatory T cells
Frontiers in Immunology, 2022 Human resident memory regulatory T cells (Tregs) exist in the normal, noninflamed skin. Except one, all previous studies analyzed skin Tregs using full-thickness human skin.
Takuya Sato +11 more
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The role of regulatory T cells in autoimmune thyroiditis
Медицинский совет, 2021 Autoimmune thyroiditis is an organ-specific autoimmune disease caused by the activation of self-reactive CD4+ T cells. Regulatory T (Treg) cells are a population of T cells that play a central role in immunological tolerance by suppressing selfreactive ...
S. I. Zhukova +4 more
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A2 adenosine receptor contributes to the development of cow’s milk protein allergy via regulating regulatory T cells [PDF]
Iranian Journal of Basic Medical Sciences, 2021 Objective(s): A2 adenosine receptor (A2AR) is a novel promising target for the treatment of inflammatory and allergic diseases. However, its role in the development of cow’s milk protein allergy (CMPA) has not been elucidated.
Chuan-Ying Li +4 more
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Foxp3: Shades of Tolerance [PDF]
Immunity, 2012 In this issue of Immunity, Darce et al. (2012) and Bettini et al. (2012) demonstrate that seemingly subtle alterations in the interaction of Foxp3 with its transcriptional partners have a ripple effect on the outcome of autoimmune phenotypes, worsening some while ameliorating others.
Chatila, Talal A., Williams, Calvin B.
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Journal of Respiration, 2023 Leukemia inhibitory factor (LIF), a member of the IL-6 cytokine family, is highly expressed throughout the body in multiple tissues and cell types. LIF is primarily known to induce the differentiation of myeloid leukemia cells, but recent studies show ...
Howard Yu +8 more
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مجله علمی دانشگاه علوم پزشکی کردستان, 2018 Background and Aim: Rheumatoid arthritis (RA) is an autoimmune disease. It seems that the function of regulatory T cells (Tregs) is compromised in RA. Foxp3 is a critical transcription factor of these cells.
Zafari P +4 more
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