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The forkhead transcription factor FoxY regulates Nanos [PDF]
Molecular Reproduction and Development, 2012 AbstractFoxY is a member of the forkhead transcription factor family that appeared enriched in the presumptive germ line of sea urchins (Ransick et al. Dev Biol 2002;246:132). Here, we test the hypothesis that FoxY is involved in germ line determination in this animal.
Jia L, Song, Gary M, Wessel
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Role of the Forkhead Transcription Factors Fd4 and Fd5 During Drosophila Leg Development
Frontiers in Cell and Developmental Biology, 2021 Appendage development requires the coordinated function of signaling pathways and transcription factors to pattern the leg along the three main axes: the antero-posterior (AP), proximo-distal (PD), and dorso-ventral (DV).
Mireya Ruiz-Losada +2 more
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Forkhead transcription factors regulate mosquito reproduction [PDF]
Insect Biochemistry and Molecular Biology, 2007 Forkhead-box (Fox) genes encode a family of transcription factors defined by a 'winged helix' DNA-binding domain. In this study we aimed to identify Fox factors that are expressed within the fat body of the yellow fever mosquito Aedes aegypti, and determine whether any of these are involved in the regulation of mosquito yolk protein gene expression ...
Immo A, Hansen +7 more
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Genetic Regulation of Vertebrate Forebrain Development by Homeobox Genes
Frontiers in Neuroscience, 2022 Forebrain development in vertebrates is regulated by transcription factors encoded by homeobox, bHLH and forkhead gene families throughout the progressive and overlapping stages of neural induction and patterning, regional specification and generation of
Ryan F. Leung +12 more
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Thiazole antibiotics target FoxM1 and induce apoptosis in human cancer cells. [PDF]
PLoS ONE, 2009 Forkhead box M1 (FoxM1) oncogenic transcription factor represents an attractive therapeutic target in the fight against cancer, because it is overexpressed in a majority of human tumors.
Uppoor G Bhat +2 more
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Nutritional Programming of Lifespan by FOXO Inhibition on Sugar-Rich Diets
Cell Reports, 2017 Summary: Consumption of unhealthy diets is exacerbating the burden of age-related ill health in aging populations. Such diets can program mammalian physiology to cause long-term, detrimental effects.
Adam J. Dobson +6 more
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Cancer Cell International, 2023 Glioma is the most aggressive and malignant type of primary brain tumor, comprises the majority of central nervous system deaths, and is categorized into different subgroups according to its histological characteristics, including astrocytomas ...
Peyman Tabnak +3 more
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Forkhead transcription factors in chronic inflammation [PDF]
The International Journal of Biochemistry & Cell Biology, 2010 Forkhead (Fox) transcription factors have been increasingly recognized to play key roles in immune homeostasis, especially Foxp3 for its role in the development and function of regulatory T cells, and Foxo family members for their regulatory role in T and B lymphocytes as well as other leukocytes.
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Molecular Cancer, 2019 Colorectal cancer (CRC) is the third most commonly occurring cancer worldwide and the fourth most frequent cause of death having an oncological origin. It has been found that transcription factors (TF) dysregulation, leading to the significant expression
Paul Laissue
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Cell Regeneration, 2021 Forkhead box (Fox) transcription factors play important roles in mammalian development and disease. However, their function in mouse somatic cell reprogramming remains unclear.
Meijun Fu +15 more
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