Results 21 to 30 of about 94,249 (285)
FoxK1 and FoxK2 in insulin regulation of cellular and mitochondrial metabolism [PDF]
, 2019 A major target of insulin signaling is the FoxO family of Forkhead transcription factors, which translocate from the nucleus to the cytoplasm following insulin-stimulated phosphorylation.
Albrechtsen, N. +15 more
core +2 more sources
The forkhead transcription factor FoxY regulates Nanos [PDF]
Molecular Reproduction and Development, 2012 AbstractFoxY is a member of the forkhead transcription factor family that appeared enriched in the presumptive germ line of sea urchins (Ransick et al. Dev Biol 2002;246:132). Here, we test the hypothesis that FoxY is involved in germ line determination in this animal.
Jia L, Song, Gary M, Wessel
openaire +2 more sources
Cancer Reports, EarlyView., 2023 Abstract Background A methodology to assess the immune microenvironment (IME) of non‐small cell lung cancer (NSCLC) has not been established, and the prognostic impact of IME factors is not yet clear. Aims This study aimed to assess the IME factors and evaluate their prognostic values. Methods and Results We assessed CD8+ tumor‐infiltrating lymphocyte (
Yukihiro Terada +16 more
wiley +1 more source
Genetic Regulation of Vertebrate Forebrain Development by Homeobox Genes
Frontiers in Neuroscience, 2022 Forebrain development in vertebrates is regulated by transcription factors encoded by homeobox, bHLH and forkhead gene families throughout the progressive and overlapping stages of neural induction and patterning, regional specification and generation of
Ryan F. Leung +12 more
doaj +1 more source
Expression and intracellular localization of FKHRL1 in mammary gland neoplasms. [PDF]
, 2004 FKHRL1 (FOXO3a), a member of the Forkhead family of genes, has been considered to be involved in the development of breast tumors; however, the in vivo expression and activation status of FKHRL1 in breast tumors still remains unclear.
Akagi, Tadaatsu +8 more
core +1 more source
Cancer Cell International, 2023 Glioma is the most aggressive and malignant type of primary brain tumor, comprises the majority of central nervous system deaths, and is categorized into different subgroups according to its histological characteristics, including astrocytomas ...
Peyman Tabnak +3 more
doaj +1 more source
Gene Structure, cDNA Sequence, and mRNA Distribution [PDF]
, 1994 The rat HNF-3 (hepatocyte nuclear factor 3) gene family encodes three transcription factors known to be important in the regulation of gene expression in liver and lung.
Hiemisch, Holger +3 more
core +1 more source
Nutritional Programming of Lifespan by FOXO Inhibition on Sugar-Rich Diets
Cell Reports, 2017 Summary: Consumption of unhealthy diets is exacerbating the burden of age-related ill health in aging populations. Such diets can program mammalian physiology to cause long-term, detrimental effects.
Adam J. Dobson +6 more
doaj +1 more source
Thiazole antibiotics target FoxM1 and induce apoptosis in human cancer cells. [PDF]
PLoS ONE, 2009 Forkhead box M1 (FoxM1) oncogenic transcription factor represents an attractive therapeutic target in the fight against cancer, because it is overexpressed in a majority of human tumors.
Uppoor G Bhat +2 more
doaj +1 more source
Roles of binding elements, FOXL2 domains, and interactions with cJUN and SMADs in regulation of FSHβ. [PDF]
, 2014 We previously identified FOXL2 as a critical component in FSHβ gene transcription. Here, we show that mice deficient in FOXL2 have lower levels of gonadotropin gene expression and fewer LH- and FSH-containing cells, but the same level of other pituitary ...
Barakat, Nermeen H +7 more
core +1 more source