Results 31 to 40 of about 121,846 (309)

Conjunctival FOXP3 expression in trachoma: do regulatory T cells have a role in human ocular Chlamydia trachomatis infection? [PDF]

, 2006
BACKGROUND: Trachoma, caused by ocular infection with Chlamydia trachomatis, remains the leading infectious cause of blindness and in 2002 was responsible for 3.6% of total global blindness.
Faal Nkoyo, Jeffries, David, Sarr Isatou, Joof Hassan, Nkoyo Faal, David Jeffries, Laye Mass, Martin J Holland, Robin L Bailey, Bailey Robin L, Bailey, Robin L, Holland, Martin J, Jeffries David, Joof, Hassan, Laye, Mass, Holland Martin J, Hassan Joof, Mass Laye, Mabey David C. W, Sarr, Isatou, David C W Mabey, Faal, Nkoyo, Isatou Sarr, Mabey, David CW   +23 more
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FOXP3-specific immunity [PDF]

OncoImmunology, 2013
Forkhead box P3 (FOXP3)-specific cytotoxic CD8+ T cells are present among human peripheral blood mononuclear cells (PBMCs), especially in cancer patients. Such T lymphocytes are able not only to specifically recognize dendritic cells (DCs) that have been exposed to recombinant FOXP3 and regulatory T cells, but also to kill FOXP3+ malignant T cells. The
openaire   +2 more sources

GARP and GARP-Treated tDC Prevented the Formation of Atherosclerotic Plaques in ApoE−/- Mice

Journal of Inflammation Research, 2021
Yifan Cai,1 Qiutang Zeng,1 Yuzhou Liu,2 Ruirui Zhu,1 Kunwu Yu,1 Wenbin Xu,1 Yue Wang,1 Yan Ding,1 Jian Yu,1 Chengliang Pan,1 Yudong Peng,1 Yi Mao,1 Peng Cheng,1 Lun Huang,1 Xiaobo Mao,1 Yucheng Zhong1 1Department of Cardiology, Union Hospital, Tongji ...
Cai Y, Zeng Q, Liu Y, Zhu R, Yu K, Xu W, Wang Y, Ding Y, Yu J, Pan C, Peng Y, Mao Y, Cheng P, Huang L, Mao X, Zhong Y   +15 more
doaj  

Prostate cancer with different ERG status may show different FOXP3-positive cell numbers [PDF]

, 2016
Prostatic carcinoma is the most frequent cancer in males in the Western world. A significant proportion of these cancers have a recurrent translocation involving ETS family genes, which leads to the overexpression of ERG transcription factor.
Krystyna Gałązka, Mateusz Rubinkiewicz, Tomasz Gołąbek, Okoń, Krzysztof, Glajcar, Anna, Karolina Kaczmarczyk-Sekuła, Gałązka, Krystyna, Piotr Chłosta, Chłosta, Piotr, Kaczmarczyk-Sekuła, Karolina, Szpor, Joanna, Szopiński, Tomasz, Dyduch, Grzegorz, Krzysztof Okoń, Joanna Szpor, Gołąbek, Tomasz, Anna Glajcar, Grzegorz Dyduch, Katarzyna Miłek, Rubinkiewicz, Mateusz, Katarzyna Tyrak, Tyrak, Katarzyna, Miłek, Katarzyna, Tomasz Szopiński   +23 more
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Prospective validation of CD4 CD25 FOXP3 T-regulatory cells as an immunological marker to differentiate intestinal tuberculosis from Crohn’s disease [PDF]

Intestinal Research, 2021
Background/Aims Crohn’s disease (CD) and intestinal tuberculosis (ITB) remain “difficult-to-differentiate” diseases. We have previously documented peripheral blood frequency of CD4+ CD25+ FOXP3+ T-regulatory cells (Treg) as a biomarker to differentiate ...
Ritika Rampal, Saurabh Kedia, Mohamad Nahidul Wari, Deepak Madhu, Amit Kumar Singh, Veena Tiwari, V. Pratap Mouli, Srikant Mohta, Govind Makharia, Vineet Ahuja   +9 more
doaj   +1 more source

Clinical Significance of FOXP3 Expression in BRCA1/2-Mutant Breast Cancer

Zhongliu Fangzhi Yanjiu
ObjectiveTo investigate the potential significance of FOXP3 expression in BRCA1/2-mutant breast cancer. MethodsA total of 48 BRCA mutation carriers (16 with BRCA1 and 32 with BRCA2) and 78 age-matched non-carriers were included in this study ...
Linxi CHEN, Li HU, Jiuan CHEN, Lu YAO, Juan ZHANG, Ye XU, Yuntao XIE   +6 more
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Effect of RUNX1/FOXP3 axis on apoptosis of T and B lymphocytes and immunosuppression in sepsis

Open Medicine, 2023
Lymphocyte apoptosis is a latent factor for immunosuppression in sepsis. Forkhead box protein P3 (FOXP3) can interact with RUNX family transcription factor 1 (RUNX1) in regulatory T cells.
Chao Yangfa, Huang Wenting, Xu Zhiheng, Li Ping, Gu Shaodong   +4 more
doaj   +1 more source

Expression of Foxp3 in colorectal cancer but not in Treg cells correlates with disease progression in patients with colorectal cancer

, 2013
Background: Regulatory T cells (Treg) expressing the transcription factor forkhead-box protein P3 (Foxp3) have been identified to counteract anti-tumor immune responses during tumor progression. Besides, Foxp3 presentation by cancer cells itself may also
Kim, Mia, Lazariotou, Maria, Gasser, Martin, Waaga, Ana Maria da Silva Rosa, Martin Gasser, Grimmig, Tanja, Heemann, Uwe, Blaheta, Roman A., Andreas Rosenwald, Igor Tsaur, Meier, Eva, Rosenwald, Andreas, Christoph-Thomas Germer, Martin Grimm, Waaga-Gasser, Ana Maria, Mia Kim, Uwe Heemann, Eva Meier, Roman Blaheta, Ana Maria Waaga-Gasser, Germer, Christoph-Thomas, Tsaur, Igor, Blaheta, Roman, Tanja Grimmig, Grimm, Martin, Maria Lazariotou   +25 more
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IPEX as a Result of Mutations in FOXP3 [PDF]

Clinical and Developmental Immunology, 2007
Immunodysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome is a rare disorder caused by mutations in theFOXP3gene that result in the defective development ofCD4+CD25+regulatory T cells which constitute an important T cell subset involved in immune homeostasis and protection against autoimmunity.
Hans J. J. van der Vliet, Edward E. Nieuwenhuis   +1 more
openaire   +3 more sources

Human CD4+ Memory T Cells Can Become CD4+IL-9+ T Cells [PDF]

, 2010
Background: IL-9 is a growth factor for T- and mast-cells that is secreted by human Th2 cells. We recently reported that IL-4+TGF-β directs mouse CD4+CD25−CD62L+ T cells to commit to inflammatory IL-9 producing CD4+ T cells.
Popoola, Joyce, Wenda Gao, Terry B Strom, Gao Wenda, Strom, Terry B., Strom Terry B., Strom, TB, Putheti, P, Popoola, J, Awasthi, A, Amit Awasthi, Awasthi Amit, Prabhakar Putheti, Popoola Joyce, Awasthi, Amit, Putheti Prabhakar, Joyce Popoola, Gao, W   +17 more
core   +1 more source