Results 51 to 60 of about 129,408 (207)

Anti-regulatory T cell vaccines in immunotherapy: focusing on FoxP3 as target

Human Vaccines & Immunotherapeutics, 2019
Anti- tumor vaccination elicits imperfect immune responses against tumor cells; that is related to the presence of suppressive obstacles in the tumor microenvironment.
Neda Mousavi-Niri, Maryam Naseroleslami, Jamshid Hadjati   +2 more
doaj   +1 more source

Evaluation of the Relationship of PD-L1 and FOXP3 Expressions With Clinicopathological Parameters in Gastric Carcinomas

Forbes Tıp Dergisi, 2021
Objective: At the time of diagnosis, gastric cancers are generally at an advanced stage and the survival rates are very low. The aim of this study is to determine the prognostic values of PD-L1 expression in gastric carcinomas and to detect the presence ...
Sevil Sayhan, Gulden Diniz, Duygu Ayaz, Dudu Solakoglu Kahraman, Pınar Ayvat, Bulent Calik   +5 more
doaj   +1 more source

FOXP3-hESC and NF1-hESC lines differentiate into cells of all three germ layers.

, 2016
(A) FOXP3-hESC and NF1-hESC lines were differentiated into endoderm, mesoderm and ectoderm. Immunofluorescence staining showed expression of SOX17, BRACHYURY and OTX2, representing differentiation into endoderm, mesoderm and ectoderm, respectively. Scale
Julie Baker (3175686), Hui Zhu (87035), Barry Behr (120359), Vikrant V. Reddy (3175683), Mark Hughes (1717240), Yuqiong Pan (227983)   +5 more
core   +1 more source

Regulatory T Cells in Cancer Immunotherapy: Basic Research Outcomes and Clinical Directions

Cancer Management and Research, 2020
Guoming Zeng,1,2,* Libo Jin,3,4,* Qinsi Ying,5 Haojie Chen,3 Murinda Charmaine Thembinkosi,3 Chunguang Yang,6 Jinlong Zhao,6 Hao Ji,3 Sue Lin,3 Renyi Peng,3 Maolan Zhang,1,3 Da Sun3 1Chongqing University of Science and Technology, Chongqing 401331 ...
Zeng G, Jin L, Ying Q, Chen H, Thembinkosi MC, Yang C, Zhao J, Ji H, Lin S, Peng R, Zhang M, Sun D   +11 more
doaj  

Depleting T regulatory cells by targeting intracellular Foxp3 with a TCR mimic antibody

OncoImmunology, 2019
Depletion of T regulatory cells (Tregs) in the tumor microenvironment is a promising cancer immunotherapy strategy. Current approaches for depleting Tregs are limited by lack of specificity and concurrent depletion of anti-tumor effector T cells.
Tao Dao, Sung Soo Mun, Andrew C. Scott, Casey A. Jarvis, Tatyana Korontsvit, Zhiyuan Yang, Lianxing Liu, Martin G. Klatt, Manuel Guerreiro, Annamalai Selvakumar, Elliott J. Brea, Claire Oh, Cheng Liu, David A. Scheinberg   +13 more
doaj   +1 more source

Expression of the mRNA of the inflammatory component of the immune response in the period of the expected window of implantation in women with recurrent pregnancy loss in the programs of assisted reproductive technologies

Репродуктивная эндокринология, 2017
The aim of study. To reveal the peculiarities of mRNA expression of the inflammatory component genes of the immune response in the expected window of the implantation in women with RPL in ART programs. Material and methods.
К. П. Головатюк, В. Г. Дубініна, О. М. Носенко, Е. Т. Макшаєва, І. Л. Головатюк-Юзефпольська   +4 more
doaj   +1 more source

Value of Foxp3 expressing T-regulatory cells in renal tissue in lupus nephritis; an immunohistochemical study [PDF]

Journal of Nephropathology, 2016
Background: Forkhead box P3 (Foxp3) functions as a master regulator in the development and function of T-regulatory (Treg) cells. Recent studies have shown that autoimmune diseases including systemic lupus erythematosus (SLE) are associated with an ...
Marwa M Shakweer, Maha Behairy, Nadia G Elhefnawy, Tamer W Elsaid   +3 more
doaj   +1 more source

Foxp3

RCSB Protein Data Bank
Citation: 'Foxp3' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13141 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +2 more sources

The role of Foxp3 and Tbet co-expressing Treg cells in lung carcinoma

OncoImmunology, 2018
Despite the opposite roles of Tbet and Foxp3 in the immune system as well as in tumour biology, recent studies have demonstrated the presence of of CD4+ T cells, expressing both, Tbet and Foxp3.
Katerina Kachler, Corinna Holzinger, Denis I. Trufa, Horia Sirbu, Susetta Finotto   +4 more
doaj   +1 more source

SUBCELLULAR LOCALIZATION OF FoxP3 TRANSCRIPTION FACTOR IN PATIENTS WITH ACUTE CORONARY SYNDROME: COMPARATIVE ANALYSIS AND PROSPECTIVE OBSERVATION

Медицинская иммунология, 2021
The key cellular and molecular factors being involved in the resolution of inflammation following acute myocardial infarction remain poorly understood.
I. V. Kologrivova, Tatiana E. Suslova, V. V. Ryabov, M. A. Shtatolkina, O. A. Koshelskaya, O. A. Trubacheva, E. S. Kravchenko   +6 more
doaj   +1 more source