Results 61 to 70 of about 134,443 (312)

SUBCELLULAR LOCALIZATION OF FoxP3 TRANSCRIPTION FACTOR IN PATIENTS WITH ACUTE CORONARY SYNDROME: COMPARATIVE ANALYSIS AND PROSPECTIVE OBSERVATION

Медицинская иммунология, 2021
The key cellular and molecular factors being involved in the resolution of inflammation following acute myocardial infarction remain poorly understood.
I. V. Kologrivova, Tatiana E. Suslova, V. V. Ryabov, M. A. Shtatolkina, O. A. Koshelskaya, O. A. Trubacheva, E. S. Kravchenko   +6 more
doaj   +1 more source

Foxp3 mutants impair Foxp3 DNA binding ability.

, 2012
293T cells were transfected with EV, WT Foxp3, K17R or K18R without or with p300 expression vectors, and 48 h later, cell lysates were harvested. (A) Equal amounts of cell lysates were incubated with biotin-labeled Foxp3 binding site nucleotide, and ...
Ulf H. Beier (188290), Rongxiang Han (188286), Yujie Liu (188278), Wayne W. Hancock (44791), Liqing Wang (188282)   +4 more
core   +1 more source

Young Tg4 FoxP3^gfpmice have unaltered levels of FoxP3 expression.

, 2013
A. FoxP3 expression by CD4+CD8− thymocytes or CD4+ cells from the spleen and mesenteric lymph nodes of male Tg4 FoxP3wt and Tg4 FoxP3gfp mice aged 5–7 weeks, directly ex vivo. Horizontal bar indicates mean. * p = 0.0329, ** p = 0.0084, n.s.
Bronwen R. Burton (400298), Johan Verhagen (400297), Graham J. Britton (400299), Ella R. Shepard (400300), Stephen M. Anderton (297580), David C. Wraith (400301)   +5 more
core   +1 more source

Biomimetic Hybrid‐Membrane Nanoreactor for Deep‐Seated Photodynamic Immunotherapy of Hepatocellular Carcinoma via Dual Catalysis‐Enhanced ROS Amplification and cGAS‐STING Activation

Advanced Functional Materials, EarlyView.
UCNP@MnOx‐Hyp@HRM (UMHM) enables tumor targeting and accumulation. Under 808 nm NIR irradiation, PDT/CDT synergistically triggers ICD and cGAS–STING immunity for deep hepatocellular carcinoma therapy. ABSTRACT Photodynamic therapy (PDT) is promising against hepatocellular carcinoma (HCC).
Wen Li, Jianzhang Luo, Pei Lu, Dongqing Liu, Huijun Yi, Xiaoyuan Yi, Bixia Chi, Wen Chen, Qingyu Zeng, Feifei He, Liyan Wang   +10 more
wiley   +1 more source

Evaluation of FOXP3 and IL10 as immunosuppressant markers in pediatric acute lymphocytic leukemia patients in Iraq [PDF]

Romanian Journal of Pediatrics
Background. Increased FOXP3+ Treg levels in the TME were positively correlated with a worse prognosis in certain cancer patients. FOXP3 was significantly overexpressed in pediatric B-ALL patients, and this overexpression was associated with a worse ...
Zainab Jasim Mohammed, Maha Kalaf Zughair, Majid Noori Humoud, Sadeq K. Ali   +3 more
doaj   +1 more source

Oxidized low-density lipoprotein increased susceptibility to primary nephrotic syndrome by regulating the Treg/Th17 ratio via MEG3 signalling

Archives of Medical Science, 2021
Introduction Patients with primary nephrotic syndrome (PNS) were reported to exhibit an evident imbalance between the number of Th17 and Treg cells in their peripheral blood monocytes (PBMCs), which might be the immunological basis of the disease ...
Li Jin, Xiaopei Wang, Xinfang Xie, Ping Lan, Shifeng Yang   +4 more
doaj   +1 more source

Correlation of Foxp3+ Treg with Foxp3+ cancer cell expression and immunohistochemical analysis of Foxp3+ Treg and Foxp3+ cancer cells.

, 2013
(A) Significant inverse correlation of Foxp3+ cancer cell expression with the Foxp3 Treg expression. Regression analysis; R2, coefficient of determination. (B) Increased numbers of Foxp3+ Treg in Foxp3 negative cancer tissue (arrow).
Roman Blaheta (285994), Tanja Grimmig (285989), Martin Gasser (285998), Andreas Rosenwald (321), Maria Lazariotou (285991), Christoph-Thomas Germer (285996), Martin Grimm (285990), Igor Tsaur (285993), Uwe Heemann (285995), Ana Maria Waaga-Gasser (285997), Mia Kim (285988), Eva Meier (285992)   +11 more
core   +1 more source

Topically Delivered Treg‐Attracting Microparticle‐Hydrogel Composites Recruit Regulatory T Cells and Limit Cardiac Injury After Severe Ischemia

Advanced Healthcare Materials, EarlyView.
CCL22‐releasing PLGA microparticles (MP) suspended in topically applied hydrogels (HEART) establish a sustained chemokine gradient at the injured myocardium. HEART recruits CCR4+ regulatory T cells, reduces infarct size and graft fibrosis, and improves cardiac function.
Matthew A. Borrelli, Alexis T. Reese, Jordan J. P. Warunek, Betsy Ann Varghese, Canxing Lin, Jeffery J. Baust, Brenda McMahon, Steven R. Little, Hēth R. Turnquist   +8 more
wiley   +1 more source

FOXP3 phosphorylation by LCK.

, 2013
(A) Phosphorylation of FOXP3 in MCF-7 cells. FOXP3 was immunoprecipitated with an anti-FLAG antibody and immunoblotted with an anti-PY-20 antibody (top). The antibodies were stripped and FOXP3-FLAG was detected using an anti-FLAG antibody (bottom). FOXP3
Nam-Soon Kim (62459), Akihiro Morita (470271), Kumiko Nakahira (470270), Itaru Yanagihara (445949)   +3 more
core   +1 more source

Downregulation of Ezh2 methyltransferase by FOXP3: New insight of FOXP3 into chromatin remodeling?

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2013
Transcription factor FOXP3 (forkhead box P3) is found initially as a key regulator in regulatory T cells. Recently its expression has been demonstrated in some non-lymphoid normal and cancerous cells. Now FOXP3 has been proven to regulate cancer-related genes, especially suppressor genes in breast cancer.
Shen, Zhu, Chen, Ling, Yang, Xiaojun, Zhao, Yun, Pier, Eric, Zhang, Xia, Yang, Xichuan, Xiong, Ya   +7 more
openaire   +2 more sources