Results 81 to 90 of about 129,408 (207)

What is the relevance of FoxP3 in the tumor microenvironment and cancer outcomes? [PDF]

Forkhead box P3 (FoxP3) transcription factor plays critical roles in controlling immune responses and cancer progression in different cancers. FoxP3 expression within the tumor microenvironment (TME) may influence clinical outcomes negatively or ...
Elkord, Eyad, Meyiah, Abdo
core   +1 more source

Young Tg4 FoxP3^gfpmice have unaltered levels of FoxP3 expression.

, 2013
A. FoxP3 expression by CD4+CD8− thymocytes or CD4+ cells from the spleen and mesenteric lymph nodes of male Tg4 FoxP3wt and Tg4 FoxP3gfp mice aged 5–7 weeks, directly ex vivo. Horizontal bar indicates mean. * p = 0.0329, ** p = 0.0084, n.s.
Bronwen R. Burton (400298), Johan Verhagen (400297), Graham J. Britton (400299), Ella R. Shepard (400300), Stephen M. Anderton (297580), David C. Wraith (400301)   +5 more
core   +1 more source

Role and specificity of regulatory T cells during retroviral infection [PDF]

, 2009
During chronic viral infection of the hematopoietic system, both virus-mediated and immune-mediated effects may cause bone marrow dysfunction leading to cytopenias. To study the pathological consequences of the T helper response to unresolving chronic
Antunes, I.L., Antunes, I L
core  

Impaired FoxP3 induction in naive Tg4 FoxP3^gfp CD4⁺ T cells.

, 2013
A. In vitro FoxP3 induction in male, naive CD4+CD62L+ T cells by stimulation with peptide and antigen-presenting cells or plate-bound anti-CD3 and anti-CD28 antibody in the presence of IL-2 and TGF-β1 for 7 days. n = 6 each for peptide stimulation, n = 8
Bronwen R. Burton (400298), Johan Verhagen (400297), Graham J. Britton (400299), Ella R. Shepard (400300), Stephen M. Anderton (297580), David C. Wraith (400301)   +5 more
core   +1 more source

The impact of molecular alterations and the immune microenvironment on the natural history of Follicular Lymphoma including transformation to Diffuse Large B cell Lymphoma [PDF]

, 2009
PhDThe natural history of follicular lymphoma is heterogeneous with numerous relapses and remissions over many years. A substantial number of patients suffer an aggressive disease course with death due to disease within 5 years of diagnosis.
Lee, Abigail Mary
core   +2 more sources

Identification of CRTH2 as a New PPARγ-Target Gene in T Cells Suggested CRTH2 Dependent Conversion of Th2 Cells as Therapeutic Concept in COVID-19 Infection

ImmunoTargets and Therapy
Antonia Becker,1 Karoline Röhrich,1 Amanda Leske,1 Ulrike Heinicke,1 Tilo Knape,2 Aimo Kannt,2,3 Verena Trümper,4 Kai Sohn,5 Annett Wilken-Schmitz,1 Holger Neb,1 Elisabeth H Adam,1 Volker Laux,2 Michael J Parnham,2 Valerie Onasch,4 Andreas Weigert,4 Kai ...
Becker A, Röhrich K, Leske A, Heinicke U, Knape T, Kannt A, Trümper V, Sohn K, Wilken-Schmitz A, Neb H, Adam EH, Laux V, Parnham MJ, Onasch V, Weigert A, Zacharowski K, von Knethen A   +16 more
doaj  

Nuclear galectin-1-FOXP3 interaction dampens the tumor-suppressive properties of FOXP3 in breast cancer

, 2018
FOXP3 is an important X-linked suppressor of breast cancer. It is reported that FOXP3 is usually mutant, absent, or cytoplasmic distribution in breast cancer cells, which increases the risk of breast cancer.
Xiaoju Li, Wei Zhang, Dong Fan, Cun Zhang, Weina Li, Wangqian Zhang, Huadong Zhao, Cheng Zeng, Zhaowei Wang, Qiang Hao, Yingqi Zhang, Kuo Zhang, Xiaochang Xue, Meng Li, Yuan Gao, Zhen Shu, Shuning Wang   +16 more
core   +1 more source

Adaptive immune crosstalk and complement dysregulation in the aging retina

Tzu Chi Medical Journal
The eye, long viewed as immune-privileged, is now recognized as a dynamic immunological environment where innate and adaptive mechanisms intersect to maintain retinal homeostasis.
Ting-Yi Lin, Ching-Yun Wang, Lawrence Chen, Shun-Ping Huang   +3 more
doaj   +1 more source

ROLE OF THE REGULATORY T CELLS IN PROGRESSION OF PROSTATE CANCER

Медицинская иммунология, 2019
The existing data on regulatory T cells (Tregs) in prostate cancer suggest that these cells may penetrate the prostate gland malignant tissue, suppressing antitumor immune response, thus promoting aggressive clinical course and low survival of the cancer
S. V. Popov, N. V. Sturov, N. V. Vorobyev, S. V. Khaidukov   +3 more
doaj   +1 more source

Transcription Factor Forkhead Box Protein 3 (FOXP3) as a Prognostic Indicator for Postoperative Outcomes in Patients with Breast Cancer: Establishment of a Prognostic Nomogram

Breast Cancer: Targets and Therapy
Chunlei Tan,1 Jinling Xu,2 Shiyuan Zhang,1 Shuqiang Liu,1 Xiaotian Yang,1 Danping Wu,1 Boqian Yu,1 Yuanxi Huang1 1Department of Breast Surgery, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, 150081, People’s Republic of China ...
Tan C, Xu J, Zhang S, Liu S, Yang X, Wu D, Yu B, Huang Y   +7 more
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