Results 1 to 10 of about 174,092 (264)

LKB1 Positively Regulates Dendritic Cell-induced T Cell Immunity and Suppresses Tumor Development [PDF]

Iranian Journal of Immunology, 2023
Background: The functions of dendritic cells (DCs) are influenced by their intracellular metabolism, in which liver kinase B1 (LKB1) plays an important role.
Wenjie Zhang, Shan Liu, Lin Zhao, Juncheng Wang, Meng Liu, Fengge Wang, Yuekang Xu   +6 more
doaj   +1 more source

Treg Cells in Ischemic Stroke: A Small Key to a Great Orchestrion [PDF]

Клиническая практика, 2023
Ischemic stroke is a global medical problem and one of the leading causes of death or disability worldwide. The main approach of ischemic stroke therapy in the most acute period, which can prevent or minimize the development of a neurological deficit, is
Oksana A. Zhukova, Daria A. Chudakova, Vladimir V. Belopasov, Еlena V. Shirshova, Vladimir P. Baklaushev, Gaukhar M. Yusubalieva   +5 more
doaj   +1 more source

The attenuation effect of low piperine Piper nigrum extract on doxorubicin-induced toxicity of blood chemical and immunological properties in mammary tumour rats

Pharmaceutical Biology, 2022
Context Many natural extracts have been shown to minimize the toxicity of doxorubicin (Dox). Low piperine Piper nigrum L. (Piperaceae) extract (PFPE) is a natural extract containing many types of antioxidants that may reduce Dox toxicities.
Jirakrit Saetang, Aman Tedasen, Surasak Sangkhathat, Natnaree Sangkaew, Sirinapa Dokduang, Napat Prompat, Siriporn Taraporn, Potchanapond Graidist   +7 more
doaj   +1 more source

Facilitating Success: Using Self-Regulated Learning and Servant Leadership in the College Classroom

Journal of Teaching and Learning with Technology, 2020
Student-centered pedagogy shifts the power dynamics, function of content, role of the educator, responsibility for learning, and purpose of evaluation (Weimer, 2013) within the classroom.
Michelle Lynn Clemons, Treg Hopkins
doaj   +1 more source

CircFLNA/miR-214 modulates regulatory T cells by regulating PD-1 in acute lung injury induced by sepsis

Autoimmunity, 2023
Sepsis-induced acute respiratory distress syndrome (ARDS) remains a major complication of death from bacterial infection. Regulatory T cells (Tregs) are important regulators in addressing lung injury.
Jian Zhong, Wei Zhang, Leiyun Zhang, Jieying Li, Lingkai Kang, Xiaoyue Li   +5 more
doaj   +1 more source

Features of parameters of cellular immune depending on the activity of foci of demyelination in children with multiple sclerosis

Медицинская иммунология, 2023
MS is a common disease of the central nervous system that leads to disability and reduced quality of life. The debut of disease in 3-5% of patients occurs in childhood and has a less favorable course compared to adults.
T. V. Radygina, D. G. Kuptsova, O. V. Kurbatova, S. V. Petrichuk, E. L. Semikina, A. P. Fisenko, L. M. Abdullaeva, B. I. Bursagova   +7 more
doaj   +1 more source

Upregulation of Cytokines and Differentiation of Th17 and Treg by Dendritic Cells: Central Role of Prostaglandin E2 Induced by Mycobacterium bovis

Microorganisms, 2020
Mycobacterium bovis (M. bovis) is a zoonotic pathogen that causes bovine and human tuberculosis. Dendritic cells play a critical role in initiating and regulating immune responses by promoting antigen-specific T-cell activation.
Han Liu, Xuekai Xiong, Wenjun Zhai, Tingting Zhu, Xiaojie Zhu, Yifan Zhu, Yongchong Peng, Yongliang Zhang, Jieru Wang, Huanchun Chen, Yingyu Chen, Aizhen Guo   +11 more
doaj   +1 more source

Do Treg Speed Up with CARs? Chimeric Antigen Receptor Treg Engineered to Induce Transplant Tolerance [PDF]

, 2023
Adoptive transfer of regulatory T cells (Treg) can induce transplant tolerance in preclinical models by suppressing alloantigen-directed inflammatory responses; clinical translation was so far hampered by the low abundance of Treg with allo-specificity ...
Kaljanac, Marcell, Abken, Hinrich
core   +1 more source

Treg-NASHcm and HFMCDm increased the inflammasome and inhibited the proliferative H9c2 cells.

, 2022
Flow cytometry-assessed relative intracellular levels (/buffer group) of (A) FXR, IL-10R, IL-10, (B) NLRP3, caspase-1 among various CM pre-treated H9c2. Bar graph of (C) immunofluorescence-assessed Ki-67+cells (red color), TUNEL+ cells (green color), and
Tzu-Hao Li (2183854), Ming-Chih Hou (383484), Shiang-Fen Huang (344337), Szu-Yu Liu (14241673), Chia-Chang Huang (806891), Tzung-Yan Lee (14241676), Han-Chieh Lin (115193), Ying-Ying Yang (474596)   +7 more
core   +1 more source

In vitro generation of regulatory T cells: A challenging tool for studying immune aging in humans [PDF]

FEBS Open Bio
In vitro induction of human regulatory T cells using standard protocols generates suppressive, Foxp3‐expressing CD4+ T cells independently of TGF‐β supplementation and donor age. Regulatory T (Treg) cells play a key role in immune tolerance and homeostasis.
Muller L, Bleher J, Weinberger B, Rocamora‐Reverte L.   +3 more
europepmc   +2 more sources