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Immune, metabolism and therapeutic targets in RA (Rheumatoid Arthritis) [PDF]
BIO Web of Conferences, 2022 Rheumatoid arthritis is a classic autoimmune disease, the pathogenesis of which is closely linked to the auto-reactivity of immune cells and joint inflammation. Three cell types, namely T cells, macrophages and fibroblast-like synoviocytes (FLS), play an
Liu Keying
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Persistent immune activation in CVID and the role of IVIg in its suppression
Frontiers in Immunology, 2014 Common variable immunodeficiency (CVID) is one of the most common and clinically important primary immune deficiencies. CVID patients have poor humoral immunity resulting in recurrent infections of the gastrointestinal and upper respiratory tracts, as ...
Dominic ePaquin-Proulx +1 more
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Frontiers in Immunology, 2020 Deoxynivalenol (DON) is a Fusarium mycotoxin that frequently contaminates the feed of farm animals. Pigs with their monogastric digestive system are in particular sensitive to DON-contaminated feed. At high concentrations, DON causes acute toxic effects,
Eleni Vatzia +5 more
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T cell aging: A review of the transcriptional changes determined from genome-wide analysis
Frontiers in Immunology, 2013 Age carries a detrimental impact on T cell function. In the past decade, analyses of the genome-scale transcriptional changes of T cells during aging have yielded a large amount of data and provided a global view of gene expression changes in T cells ...
Guobing eChen +2 more
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eLife, 2020 The female reproductive tract (FRT) is the most common site of infection during HIV transmission to women, but viral remodeling complicates characterization of cells targeted for infection.
Tongcui Ma +8 more
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T–cell anergy and peripheral T–cell tolerance [PDF]
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2001 The discovery that T–cell recognition of antigen can have distinct outcomes has advanced understanding of peripheral T–cell tolerance, and opened up new possibilities in immunotherapy. Anergy is one such outcome, and results from partial T–cell activation.
R, Lechler +3 more
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The T‐cell receptor repertoire of regulatory T cells [PDF]
Immunology, 2008 SummaryThe CD4+ CD25+ regulatory population of T cells (Treg cells), which expresses the forkhead family transcription factor (Foxp3), is the key component of the peripheral tolerance mechanism that protects us from a variety of autoimmune diseases.
Rafal, Pacholczyk, Joanna, Kern
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Naïve, Effector, and Memory T cells Frequency in the Peripheral Blood of Healthy Men Following 4 Weeks of Intermittent Fasting [PDF]
International Journal of Nutrition SciencesBackground: Intermittent fasting (IF) is a 16/8 fasting model, which is supposed to recruit immune cells to the bone marrow, thus prevents immune exhaustion.
Sara Assadiasl +7 more
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Gynura procumbens ethanol extract and its fractions inhibit Th1, Th2 and Th17 but induce Treg cells differentiation during atherosclerosis development [PDF]
Journal of HerbMed Pharmacology, 2021 Introduction: Gynura procumbens (Lorr.) Merr. (GP) displays cardio-protective effect, which may hinder atherogenesis induced by oxidized low-density lipoprotein (oxLDL) and leukocytes.
Manimegalai Manogaran +3 more
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T lymphocytes development and aging
生物医学转化, 2023 T lymphocytes, as a vital component of the adaptive immune system, play a crucial role in maintaining immune health. A thorough investigation of their maturation and aging processes is essential for achieving a comprehensive understanding of the immune ...
Mao Lipeng, Luo Junhong, Chen Guobing
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