Results 21 to 30 of about 167,295 (312)
The Effect of Schisandrin B on the Development of Multiple Sclerosis
Proceedings, 2019 Multiple Sclerosis (MS) is a chronic inflammatory, demyelinating neurodegenerative disease targeting the central nervous system. The pathogenesis of MS is a process of innate and adaptive immune system components.
Mustafa Cakir +3 more
doaj +1 more source
, 2021 International audienceCD4+Foxp3+ regulatory T (Treg) cells are central modulators of autoimmune diseases. However, the timing and location of Treg cell-mediated suppression of tissue-specific autoimmunity remain undefined.
Kassem, Sahar +19 more
core +1 more source
The Journal of Reproduction and Development, 2021 Immune imbalance of Treg/Th17 cells may contribute to recurrent implantation failure (RIF) during in vitro fertilization and embryo transfer (IVF-ET). In this study, we sought to determine the effect of intrauterine administration of mouse PBMCs prior to
Lei FAN +6 more
doaj +1 more source
Memorias do Instituto Oswaldo Cruz, 2012 The interleukin (IL)-2R alpha chain (CD25) is expressed on regulatory T cells (Treg), which constitute more than 85% of the CD25+ T cell population in a naïve mouse.
Haroon Akbar +4 more
doaj +1 more source
, 2009 The potential use of CD4(+)Foxp3(+) Treg as a cellular therapy for autoimmune disease is of great interest. For clinical translation, the key objective is to reverse established disease.
Stephens LA +5 more
core +2 more sources
, 2022 Lupus nephritis (LN) is a severe consequence of systemic lupus erythematosus (SLE) and is an important driver of morbidity and mortality in SLE. Treg cells and TIM-3 play an important role in the pathogenesis of LN.
Xiao-shuang Zhou +3 more
core +1 more source
Frequency of CD39+, LAG3+, and CTLA4+ Regulatory T Cells in Two Different Immunosuppressive Protocols in Renal Allograft Recipients (Sirolimus vs Mycophenolate mofetil): A Cohort Report [PDF]
Iranian Journal of Immunology, 2022 Background: Impaired renal function is considered as a significant risk factor for cardiovascular events in chronic kidney disease patients. Several immunosuppressive drugs are used in these patients, which necessitates to minimize the drug-related side ...
Yaghoub Mollaei-Kandelous +7 more
doaj +1 more source
The T-Cell Response to Type 2 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)
Viruses, 2019 Porcine reproductive and respiratory syndrome virus (PRRSV) continues to cause severe reproductive and respiratory pathologies resulting in immense monetary and welfare costs for the swine industry.
Andrew R. Kick +6 more
doaj +1 more source
The FASEB Journal, 2018 Naïve CD4+ Th (T helper cells) can differentiate/be polarized in to 9 terminally differentiated Th cell subsets depending on the cytokine repertoire and anatomical location. CD4+ FOXP3+ (forkhead box P3) regulatory T cells (Treg) are one of the Th subsets.
Keman Xu +8 more
openaire +1 more source
Super-Treg: Toward a New Era of Adoptive Treg Therapy Enabled by Genetic Modifications
, 2021 International audienceRegulatory Tcells (Treg) are essential components of peripheral immune homeostasis. Adoptive Treg cell therapy has shown efficacy in a variety of immune-mediated diseases in preclinical studies and is now moving from phase I/IIa to ...
Amini, Leila +8 more
core +1 more source