Results 11 to 20 of about 174,092 (264)

Regulatory T-cells and allogeneic hematopoietic stem cell transplantation

Трансплантология (Москва), 2022
The article has summarized the available data about regulatory T cells, describing in-detail the stages of their studying, their development, classification, mechanisms of immunosuppression in general terms and also in the context of allogeneic ...
O. S. Karavaeva, M. Yu. Drokov, E. G. Khamaganova   +2 more
doaj   +1 more source

IL-6 controls susceptibility to helminth infection by impeding Th2 responsiveness and altering the Treg phenotype in vivo [PDF]

, 2014
IL-6 plays a pivotal role in favoring T-cell commitment toward a Th17 cell rather than Treg-cell phenotype, as established through in vitro model systems.
Maizels, Rick M., Katherine A. Smith, Maizels, Rick M, Rick M. Maizels, Smith, Katherine A., Smith, Katherine A   +5 more
core   +1 more source

The role of galectin-1 and galectin-3 in the mechanisms of T-cell immune response dysregulation in colon cancer

Бюллетень сибирской медицины, 2020
The aim of the study was to characterize the features of the subpopulation composition and cytokine-secretory activity of T lymphocytes (Th1, Th17 and Treg) in relation to the concentration of galectin-1 and galectin-3 in the blood of patients with colon
V. S. Poletika, Yu. V. Kolobovnikova, O. I. Urazova, O. A. Vasileva, A. I. Dmitrieva, K. I. Yankovich, V. V. Novitsky, L. M. Ryabova, M. Yu. Grishchenko   +8 more
doaj   +1 more source

Commentary: preclinical efficacy of immune-checkpoint monotherapy does not recapitulate corresponding biomarkers-based clinical predictions in glioblastoma by Garg et al. (2017)

OncoImmunology, 2019
Preclinical modeling and gene expression analyses have yielded distinct observations for the role of immune checkpoint, IDO1, in glioblastoma (GBM). Accordingly, our recent work differs with Garg et al.
Lijie Zhai, Erik Ladomersky, Kristen L. Lauing, Meijing Wu, Denise M. Scholtens, Rohan Savoor, Bin Zhang, Jennifer D. Wu, Craig Horbinski, Rimas V. Lukas, David C. Binder, Derek A. Wainwright   +11 more
doaj   +1 more source

The Effect of Alantolactone on the Development of Multiple Sclerosis

Proceedings, 2019
Multiple Sclerosis (MS) is a chronic inflammatory, demyelinating neurodegenerative disease targeting the central nervous system. The pathogenesis of MS is an immune mediated process involving innate and adaptive immune system components.
Mustafa Cakir, Mehmet Onder Karayigit, Ahmet Eken, Hamiyet Donmez-Altuntas   +3 more
doaj   +1 more source

HMGB1/TLR4 Signaling Affects Regulatory T Cells in Acute Lung Injury

Journal of Inflammation Research, 2021
Min Zhou,1,* Yadi Zhang,2,* Rui Tang,1 Haiyan Liu,1 Min Du,1 Zhi Gao,1 Zongshu Ji,1 Haoshu Fang3 1Neurocritical Care Unit, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei,
Zhou M, Zhang Y, Tang R, Liu H, Du M, Gao Z, Ji Z, Fang H   +7 more
doaj  

The Effect of Schisandrin B on the Development of Multiple Sclerosis

Proceedings, 2019
Multiple Sclerosis (MS) is a chronic inflammatory, demyelinating neurodegenerative disease targeting the central nervous system. The pathogenesis of MS is a process of innate and adaptive immune system components.
Mustafa Cakir, Mehmet Onder Karayigit, Ahmet Eken, Hamiyet Donmez-Altuntas   +3 more
doaj   +1 more source

Intrauterine administration of peripheral blood mononuclear cells (PBMCs) improves embryo implantation in mice by regulating local Treg/Th17 cell balance

The Journal of Reproduction and Development, 2021
Immune imbalance of Treg/Th17 cells may contribute to recurrent implantation failure (RIF) during in vitro fertilization and embryo transfer (IVF-ET). In this study, we sought to determine the effect of intrauterine administration of mouse PBMCs prior to
Lei FAN, Menghan SHA, Wei LI, Qingling KANG, Jianli WU, Suhua CHEN, Nan YU   +6 more
doaj   +1 more source

Depletion of CD25+ cells during acute toxoplasmosis does not significantly increase mortality in Swiss OF1 mice

Memorias do Instituto Oswaldo Cruz, 2012
The interleukin (IL)-2R alpha chain (CD25) is expressed on regulatory T cells (Treg), which constitute more than 85% of the CD25+ T cell population in a naïve mouse.
Haroon Akbar, Stéphanie Germon, Patricia Berthon, Isabelle Dimier-Poisson, Nathalie Moiré   +4 more
doaj   +1 more source

Treg

, 2009
Treg are immune cells that play a critical role in the regulation of the immune response. Although the transcription factor Foxp3 is widely accepted as the standard marker of Treg, specific surface markers are needed to better characterize these cells ...
Jacquelin, Sébastien, MacIntyre, Elizabeth, Pierre Milpied, Sébastien Jacquelin, Yves Lepelletier, Renand, Amédée, Rubio, Marie-Thérèse, Amédée Renand, Hermine, Olivier, Mendes-da-Cruz, Daniella A., Elizabeth MacIntyre, Olivier Hermine, Julie Bruneau, Marie‐Thérèse Rubio, Daniella A. Mendes‐Da‐Cruz, Milpied, Pierre, Vahid Asnafi, Lepelletier, Yves, Bruneau, Julie, Asnafi, Vahid   +19 more
core   +2 more sources