Results 71 to 80 of about 129,408 (207)
, 2013 (A) Significant inverse correlation of Foxp3+ cancer cell expression with the Foxp3 Treg expression. Regression analysis; R2, coefficient of determination. (B) Increased numbers of Foxp3+ Treg in Foxp3 negative cancer tissue (arrow).
Roman Blaheta (285994) +11 more
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Dysregulation of Foxp3-upregulated and Foxp3-downregulated genes by Foxp3 ProR subdomain mutations.
, 2015 P values were calculated with binomial tests to compare the distribution of Foxp3-upregulated and—downregulated genes with the distribution within all 2,407 Foxp3-regulated, TReg-relevant genes.Dysregulation of Foxp3-upregulated and Foxp3-downregulated ...
Xin Xie (311744) +6 more
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High expression of FOXP3 in primary melanoma is associated with tumour progression. [PDF]
, 2014 BACKGROUND The antitumour immune response plays an important role in the prognosis of melanoma. High numbers of circulating regulatory T cells have been associated with rapid disease progression.
Gerber, A L +6 more
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Effect of RUNX1/FOXP3 axis on apoptosis of T and B lymphocytes and immunosuppression in sepsis
Open Medicine, 2023 Lymphocyte apoptosis is a latent factor for immunosuppression in sepsis. Forkhead box protein P3 (FOXP3) can interact with RUNX family transcription factor 1 (RUNX1) in regulatory T cells.
Chao Yangfa +4 more
doaj +1 more source
Ex-Th17 Foxp3+ T cells - a novel subset of Foxp3+ T cells induced in cancer [PDF]
, 2015 Th17 and regulatory T (Treg) cells are integral in maintaining immune homeostasis and Th17-Treg misbalance associates with inflammation.\ud \ud We demonstrate that in addition to natural (n)Treg and induced (i)Treg cells developed from naïve precursors ...
Bartlett, David L +15 more
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, 2013 (A) Phosphorylation of FOXP3 in MCF-7 cells. FOXP3 was immunoprecipitated with an anti-FLAG antibody and immunoblotted with an anti-PY-20 antibody (top). The antibodies were stripped and FOXP3-FLAG was detected using an anti-FLAG antibody (bottom). FOXP3
Nam-Soon Kim (62459) +3 more
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Autoimmunity, 2020 Background Cows’ milk allergy (CMA) is a hypersensitivity immune reaction brought on by specific immunologic mechanisms to cow’s milk proteins. As one of the most common food allergies in infants, the incidence of CMA during the first year of life is ...
Beibei Sun +5 more
doaj +1 more source
Immune regulation and therapeutic application of T regulatory cells in liver diseases
Frontiers in ImmunologyCD4+ CD25+ FOXP3+ T regulatory cells (Tregs) are a subset of the immunomodulatory cell population that can inhibit both innate and adaptive immunity by various regulatory mechanisms.
Ananya Ajith +9 more
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SIRT1 regulates Foxp3 degradation.
, 2013 (A) HEK293 cells were co-transfected with HA-Foxp3 and Flag-SIRT1 and treated with 2 µM MG132 for 16 hours. Cells were lysed and Foxp3 protein levels were visualized by Western blotting using anti-HA antibodies.
Jorg van Loosdregt (352938) +5 more
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Cyclin kinase inhibitor p21: a mediator of immune tolerance: direct and indirect evidence [PDF]
, 2009 *Background:* Uncontrolled proliferation of T-cells is considered a barrier to the induction of transplantation tolerance by T regulatory cells. Therefore, cyclin kinase inhibitor p21, one of the most potent inhibitors of cell proliferation, may exert an
Ashwani Khanna
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