Results 301 to 310 of about 1,958,413 (325)
Some of the next articles are maybe not open access.
Annual Review of Immunology, 2020
Foxp3-expressing CD4+regulatory T (Treg) cells play key roles in the prevention of autoimmunity and the maintenance of immune homeostasis and represent a major barrier to the induction of robust antitumor immune responses. Thus, a clear understanding of the mechanisms coordinating Treg cell differentiation is crucial for understanding numerous facets ...
Peter A, Savage +2 more
openaire +2 more sources
Foxp3-expressing CD4+regulatory T (Treg) cells play key roles in the prevention of autoimmunity and the maintenance of immune homeostasis and represent a major barrier to the induction of robust antitumor immune responses. Thus, a clear understanding of the mechanisms coordinating Treg cell differentiation is crucial for understanding numerous facets ...
Peter A, Savage +2 more
openaire +2 more sources
Nature Reviews Immunology, 2023
The brain, long thought to be isolated from the peripheral immune system, is increasingly recognized to be integrated into a systemic immunological network. These conduits of immune-brain interaction and immunosurveillance processes necessitate the presence of complementary immunoregulatory mechanisms, of which brain regulatory T cells (Treg cells) are
Adrian Liston +3 more
openaire +4 more sources
The brain, long thought to be isolated from the peripheral immune system, is increasingly recognized to be integrated into a systemic immunological network. These conduits of immune-brain interaction and immunosurveillance processes necessitate the presence of complementary immunoregulatory mechanisms, of which brain regulatory T cells (Treg cells) are
Adrian Liston +3 more
openaire +4 more sources
2021
Mucosal surfaces are distinctive sites exposed to environmental, dietary, and microbial antigens. Particularly in the gut, the host continuously actively adapts via complex interactions between the microbiota and dietary compounds and immune and other tissue cells.
Vanessa R, Figliuolo da Paz +2 more
openaire +2 more sources
Mucosal surfaces are distinctive sites exposed to environmental, dietary, and microbial antigens. Particularly in the gut, the host continuously actively adapts via complex interactions between the microbiota and dietary compounds and immune and other tissue cells.
Vanessa R, Figliuolo da Paz +2 more
openaire +2 more sources
Autoimmunity Reviews, 2005
Several types of T regulatory (Treg) cells have been described in both mice and humans, including natural or professional (CD4+CD25+ T cells) and adaptive (Th3 and Tr1 cells) Treg cells. The former develops in the thymus and results in an endogeneous long-lived population of self-antigen-specific T cells in the periphery poised to prevent potentially ...
MAGGI, ENRICO +5 more
openaire +3 more sources
Several types of T regulatory (Treg) cells have been described in both mice and humans, including natural or professional (CD4+CD25+ T cells) and adaptive (Th3 and Tr1 cells) Treg cells. The former develops in the thymus and results in an endogeneous long-lived population of self-antigen-specific T cells in the periphery poised to prevent potentially ...
MAGGI, ENRICO +5 more
openaire +3 more sources
Immunological Reviews, 2016
SummaryPathogen exposure elicits production of high‐affinity antibodies stimulated by T follicular helper (Tfh) cells in the germinal center reaction. Tfh cells provide both costimulation and stimulatory cytokines to B cells to facilitate affinity maturation, class switch recombination, and plasma cell differentiation within the germinal center.
Peter T, Sage, Arlene H, Sharpe
openaire +2 more sources
SummaryPathogen exposure elicits production of high‐affinity antibodies stimulated by T follicular helper (Tfh) cells in the germinal center reaction. Tfh cells provide both costimulation and stimulatory cytokines to B cells to facilitate affinity maturation, class switch recombination, and plasma cell differentiation within the germinal center.
Peter T, Sage, Arlene H, Sharpe
openaire +2 more sources
Targeted Oncology, 2012
Cancers express tumor-associated antigens that should elicit immune response to antagonize the tumor growth, but spontaneous immune rejection of established cancer is rare, suggesting an immunosuppressive environment hindering host antitumor immunity.
Ménétrier-Caux, Christine +5 more
openaire +3 more sources
Cancers express tumor-associated antigens that should elicit immune response to antagonize the tumor growth, but spontaneous immune rejection of established cancer is rare, suggesting an immunosuppressive environment hindering host antitumor immunity.
Ménétrier-Caux, Christine +5 more
openaire +3 more sources
Annales de dermatologie et de venereologie, 2007
International ...
Aubin, François, Saas, Philippe
openaire +4 more sources
International ...
Aubin, François, Saas, Philippe
openaire +4 more sources
The Cancer Journal, 2010
Regulatory T cells inhibit cellular immunity and represent an obstacle for the development of cancer immunotherapy. The understanding of Treg cellular biology has exponentially increased during the last 10 years, driven primarily by elegant in vivo studies of mouse models systems and in vitro studies of human cells.
Tatiana N, Golovina +1 more
openaire +2 more sources
Regulatory T cells inhibit cellular immunity and represent an obstacle for the development of cancer immunotherapy. The understanding of Treg cellular biology has exponentially increased during the last 10 years, driven primarily by elegant in vivo studies of mouse models systems and in vitro studies of human cells.
Tatiana N, Golovina +1 more
openaire +2 more sources