Results 331 to 340 of about 613,406 (360)

Perspectives on the regulatory biology of the B lymphocyte

Folia Microbiologica, 1985
B lymphocytes with receptors specific for a particular hapten have been prepared through an antigen-affinity procedure. Methods have been developed for the clonal stimulation of these cells in vitro, with a single, hapten-specific B cell as the unequivocal target.
openaire   +3 more sources

Regulatory function of human CD4+ cytolytic T lymphocytes

Transplant Immunology, 1999
Allograft rejection is mediated by both CD4+ and CD8+ T cells. The lytic function of the classic CD8+ cytolytic T lymphocytes (CTL) occurs through recognition of allogeneic major histocompatibility complex (MHC) class I on the surface of the graft. CD4+ CTL recognize MHC class II through a direct recognition pathway or an indirect pathway where MHC ...
Nancy J. Poindexter, Arthur E Haynes, Michael A. Smith, T. Mohanakumar   +3 more
openaire   +3 more sources

Regulatory Lymphocytes in T Cell Functions in Chickens

1977
Our contemporary understanding of the immune system involves the concept of two distinct expressions of immunity as well as the division of lymphocyte types into functional subpopulations. Inherent in the development of this complexity is the discernment that some form of control mechanism must have evolved simultaneously.
openaire   +3 more sources

Murine CD8+ regulatory T lymphocytes: The new era

Human Immunology, 2008
Regulatory T lymphocytes unequivocally play a major role in the maintenance of immunologic homeostasis. The first descriptions of regulatory T lymphocytes concerned CD8(+) cells, but this field was brought into discredit when some of its central tenets turned out to be erroneous. CD4(+) regulatory T cells took over and, with the help of newly developed
Ingrid Ménager-Marcq, Ingrid Ménager-Marcq, Céline Pomié, Joost P. M. van Meerwijk, Joost P. M. van Meerwijk, Joost P. M. van Meerwijk   +5 more
openaire   +3 more sources

Role of α-fetoprotein in differentiation of regulatory T lymphocytes

Doklady Biological Sciences, 2017
The effect of native α-fetoprotein (AFP) on the expression of T-regulatory lymphocyte (Treg) markers by activated CD4+ lymphocytes with different proliferative status was studied. α-Fetoprotein did not affect the ratio of proliferating and non-proliferating activated CD4+ cells.
Valery A. Chereshnev, Valery A. Chereshnev, S. A. Zamorina, P. V. Khramtsov, M. S. Bochkova, V. P. Timganova, Maria Kropaneva, M. B. Raev, M. B. Raev   +8 more
openaire   +3 more sources

Effector and Regulatory Lymphocytes in Asthmatic Pregnant Women

American Journal of Reproductive Immunology, 2010
Citation Bohács A, Cseh Á, Stenczer B, Müller V, Gálffy G, Molvarec A, Rigó J Jr, Losonczy G, Vásárhelyi B, Tamási L. Effector and regulatory lymphocytes in asthmatic pregnant women. Am J Reprod Immunol 2010; 64: 393–401Problem  Asthma influences pregnancy outcome and pregnancy affects asthma severity, but the immunologic mechanisms of these ...
Áron Cseh, Veronika Müller, Gabriella Gálffy, Barna Vásárhelyi, György Losonczy, János Rigó, Anikó Bohács, Attila Molvarec, Lilla Tamási, Balázs Stenczer   +9 more
openaire   +3 more sources

Mechanisms of Surveillance of Dendritic Cells by Regulatory T Lymphocytes

2015
Regulatory T cells (Tregs) are critical to maintain the homeostasis of the organism, i.e., to prevent (excessive) inflammatory reactions against self and nonself. Data in the literature suggest that a variety of suppressive mechanisms exist that may act selectively depending on the tissue environment. An interesting question is whether dendritic cells (
Maxime Dhainaut, Muriel Moser
openaire   +3 more sources

Contingent Genetic Regulatory Events in T Lymphocyte Activation

Science, 1989
Interaction of antigen in the proper histocompatibility context with the T lymphocyte antigen receptor leads to an orderly series of events resulting in morphologic change, proliferation, and the acquisition of immunologic function. In most T lymphocytes two signals are required to initiate this process, one supplied by the antigen receptor and the ...
openaire   +3 more sources

Regulatory factors for initial T lymphocyte lineage specification

Current Opinion in Hematology, 2007
Initiation of T lymphocyte development depends on balanced regulatory inputs from multiple essential transcription factors. This review highlights contributions of E2A, hematopoietic transcription factor PU.1, growth factor independence (Gfi)-1, T cell factor (TCF)-1, and Runx factors and their interactions with the Notch pathway to promote T cell ...
openaire   +4 more sources

The Regulatory Role of T Lymphocytes in Wound Healing

The Journal of Trauma: Injury, Infection, and Critical Care, 1990
M. C. Regan, Adrian Barbul
openaire   +3 more sources